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OpenTrials
Completed

NCT Number: NCT02180620

Pre-dinner vs. Post-dinner Exercise on Glycemic Control

With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.

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Key information

Conditions

Type 2 Diabetes Diabetes Mellitus Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

25 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for ~5.75 h while the participants were in the lab.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Obese ( body mass index 30-45 kg/m2)
  • Physician diagnosed with type 2 diabetes receiving standard medical care
  • Non-smokers
  • Pregnancy
  • Lactating mothers

Exclusion criteria

  • Insulin
  • Surgical weight loss
  • Orthopedic limitations to exercise
  • Weight loss in the previous 3 months

Treatment and study plan

No exercise

Other

During the no exercise trial (NoEX), the participants will remain sedentary during testing.

Other names: NoEX

Meal then exercise

Other

During the post-meal exercise trial (M→EX), 45 min of resistance training will be performed

Other names: M-EX

exercise then meal

Other

During the exercise prior to the meal trial (EX→M), 45 min of resistance training will be performed

Other names: EX-M

Primary outcomes

  1. glucose concentrations

    Time frame: Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h

Secondary outcomes

  1. triglyceride concentrations

    Time frame: Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h

Other outcomes

  1. GLP-1 concentrations

    Time frame: Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h

Sponsors and collaborators

Lead sponsor

University of Missouri-Columbia

Other

Registry information

Official study title

Exercise Timing and Postprandial Glycemia in Type 2 Diabetes

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Jul 2, 2014
Registry last updated
Jun 8, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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