Practice of Deep Venous Thrombosis Prophylaxis and Its Incidence in Patients Undergoing Gastrointestinal and Hepatobiliary Surgery

Recent studies from Asia have reported a wide variation in the incidence of deep vein thrombosis (DVT), ranging from 5% to 50% in patients undergoing major abdominal surgery. However, data specific to the Nepalese population remains unavailable. This study aims to evaluate current thromboprophylaxis practices and determine the incidence of DVT in Nepalese adults undergoing gastrointestinal and hepatobiliary surgery.

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Key information

Conditions

Gastrointestinal

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Maharajgunj Medical Campus

Kathmandu, Nepal

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults aged >18 years
Underwent major gastrointestinal or hepatobiliary surgery
Surgery performed under general anesthesia
Major surgery defined as any operative intervention in the abdominal or hepatobiliary region requiring general anesthesia

Exclusion criteria

History of VTE within 3 months before surgery
Known hypercoagulable state or congenital thrombophilia
Diagnosis of atrial fibrillation
Undergoing systemic cancer chemotherapy or radiotherapy within the past 15 days
Pregnant or lactating women
Missing information in clinical records
Non-operated patients or those receiving conservative management
Patients undergoing liver transplantation

Treatment and study plan

major gastrointestinal or hepatobiliary surgery under general anesthesia

Procedure

major gastrointestinal or hepatobiliary surgery under general anesthesia

Primary outcomes

Use of Thromboprophylaxis and Incidence of DVT in Major GI and Hepatobiliary Surgeries

Time frame: From date of surgery until hospital discharge or up to 30 days postoperatively, whichever occurs first

This outcome assesses the proportion of patients receiving appropriate thromboprophylaxis, as well as the incidence of deep vein thrombosis (DVT) among individuals undergoing major gastrointestinal and hepatobiliary surgeries. Data will be collected to evaluate adherence to prophylaxis guidelines and to determine the effectiveness of thromboprophylactic measures in preventing DVT in this surgical population.

Sponsors and collaborators

Lead sponsor

Maharajgunj Medical Campus

Other

Registry information

Official study title

Practice of Deep Venous Thrombosis Prophylaxis and Its Incidence in Patients Undergoing Gastrointestinal and Hepatobiliary Surgery: A Nepalese Single-center, Retrospective Study

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Jul 28, 2025
Registry last updated: Jul 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed