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OpenTrials
Completed

NCT Number: NCT05619952

Postprandial Lipemia and Glycemia Following a High-Fat Meal

The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults, aged 18 to 35.

Completed

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Key information

Conditions

Hypercholesterolemia Dyslipidemias Glucose Metabolism Disorders Hyperglycemia Hyperlipidemias Lipid Disorder Lipid Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Postprandial Hyperglycemia

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • generally healthy
  • non-diabetic
  • normal to mildly hypercholesterolemic (Total Cholesterol 200-239 mg/dL and LDL-C 130-159 mg/dL)
  • have BMI <30 or BF% (men <25%, women <32%)
  • no known disease of the liver or gallbladder
  • no documented problems with fat metabolism
  • normal lipemic response to a lipid challenge
  • No known mushroom allergy

Exclusion criteria

  • diabetic
  • pregnant
  • BMI >30
  • liver disease
  • gallbladder disease
  • mushroom allergy
  • lipid disorder

Treatment and study plan

Mushroom Powder

Dietary Supplement

Ground shiitake mushrooms or ground white button mushrooms

Primary outcomes

  1. Postprandial Lipemia

    Time frame: Baseline, up to 6 hours postprandial

    Total cholesterol, LDL, HDL, triglycerides

  2. Postprandial Glycemia

    Time frame: Baseline, up to 6 hours postprandial

    blood glucose

Sponsors and collaborators

Lead sponsor

State University of New York at Buffalo

Other

Registry information

Official study title

Acute Effects of White Button and Shiitake Mushroom Powder Supplementation on Postprandial Lipemia and Glycemia Following a High-Fat Meal

Important dates

Study start
2014
Primary completion
2016
Study completion
2022
First posted
Nov 17, 2022
Registry last updated
Mar 27, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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