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OpenTrials
Completed

NCT Number: NCT00917878

Postprandial Effects of Milk and Milk Constituents

The purpose of this study is to determine whether the addition of milk or the milk constituents calcium and protein to a high-fat breakfast affects the postprandial lipid and inflammatory response.

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Key information

Conditions

Hyperlipidemia Body Weight Dyslipidemias Hyperlipidemias Inflammation Lipid Metabolism Disorders Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathologic Processes Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Maastricht University Medical Center

Maastricht, Netherlands

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Body mass index (BMI) above 27 kg/m2

Exclusion criteria

  • Smoking
  • Diabetes mellitus
  • Cardiovascular diseases
  • Familial hypercholesterolemia or lipid lowering medication
  • Severe conditions that might interfere with the study outcomes, such as COPD, asthma, rheumatoid arthritis, etc.
  • Unstable body weight
  • Abuse of alcohol or drugs
  • Participation in another biomedical study during the past 30 days
  • Having donated blood during the past 30 days

Treatment and study plan

Milk

Dietary Supplement

500 mL low-fat milk added to high-fat meal

Protein

Dietary Supplement

Milk protein in 500 mL water added to high-fat meal

Calcium

Dietary Supplement

Milk calcium in 500 mL water added to high-fat meal

Control

Dietary Supplement

Lactose in 500 mL water added to high-fat meal

Primary outcomes

  1. Plasma inflammatory markers

    Time frame: 6 h after meal

Secondary outcomes

  1. Serum lipids

    Time frame: 6 h after meal

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Collaborators

  • Nederlandse Zuivel Organisatie

Registry information

Official study title

The Effects of Milk and Milk Constituents on Postprandial Inflammation in Overweight Subjects

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Jun 10, 2009
Registry last updated
Apr 27, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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