Postoperative SpO₂/FiO₂ Ratio and Analgesic Methods in Laparoscopic Surgery

This prospective observational study aims to evaluate the association between postoperative oxygenation, assessed by the SpO₂/FiO₂ ratio, and body mass index (BMI), STOP-BANG score, and postoperative analgesic methods in patients undergoing elective laparoscopic cholecystectomy in the reverse Trendelenburg position. Postoperative SpO₂ and FiO₂ values will be recorded within the first postoperative hour, and the SpO₂/FiO₂ ratio will be calculated. Analgesic techniques applied as part of routine clinical practice will be documented. The study does not involve any additional intervention beyond standard care. The findings are expected to contribute to a better understanding of factors associated with early postoperative oxygenation and hypoxemia risk.

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Key information

Conditions

Postoperative Hypoxemia

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Istinye Üniversity

Istanbul, Merkez Mahallesi, 34250, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥ 18 years
Patients who provide written informed consent
ASA physical status I-III
Patients undergoing elective laparoscopic cholecystectomy
Surgery performed in the reverse Trendelenburg position (30°)
Expected operative duration < 3 hours
Exclusion Criteria:
Age < 18 years
Refusal or inability to provide informed consent
ASA physical status IV or higher
Known chronic respiratory diseases (e.g., asthma, COPD)
Severe cardiac failure (NYHA class III-IV) or advanced cardiovascular disease
Emergency surgery
Preoperative oxygen supplementation or baseline SpO₂ < 90%
Prolonged intubation or perioperative respiratory complications
Requirement for postoperative noninvasive ventilation or intensive care unit admission
Missing SpO₂ or FiO₂ data preventing calculation of the SpO₂/FiO₂ ratio

Treatment and study plan

Standard of care

Other

No intervention is applied in this study. Patients are managed according to routine clinical practice. Demographic data, body mass index, STOP-BANG score, postoperative analgesic methods, and postoperative SpO₂ and FiO₂ values are recorded, and the SpO₂/FiO₂ ratio is calculated. All data are collected observationally without any additional procedures or changes to standard care.

Primary outcomes

postoperative SpO₂/FiO₂ Ratio

Time frame: Within the first postoperative hour (0-60 minutes after surgery)

The SpO₂/FiO₂ ratio calculated using peripheral oxygen saturation (SpO₂) and fraction of inspired oxygen (FiO₂) measured during the early postoperative period to assess postoperative oxygenation.

Study contacts

Contact information is provided by the study sponsor or research team.

ilke dolğun

CONTACT

[email protected]

+905555485632

Sponsors and collaborators

Lead sponsor

Istinye University

Other

Registry information

Official study title

Association of Postoperative SpO₂/FiO₂ Ratio With Body Mass Index, STOP-BANG Score, and Analgesic Methods in Patients Undergoing Laparoscopic Surgery in Reverse Trendelenburg Position

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Feb 10, 2026
Registry last updated: Feb 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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