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OpenTrials
Completed

NCT Number: NCT00913068

Postoperative Pain Control for Prostatectomy

The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.

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Key information

Conditions

Prostate Cancer Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Male Urogenital Diseases Neoplasms Neoplasms by Site Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

Up to 80 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Queen Elizabeth Health Sciences Centre

Halifax, Nova Scotia, B3H 2Y9, Canada

About this study

Our current post operative analgesic strategy involves a multi-modal approach, using local injectable anesthetic around the incision and systemic medications (i.e. non-steroidal anti-inflammatories, acetaminophen and break-through doses of opiates). As the amount of opiates used can be significant, we have to be aware of their inherent risks. Opiates have an excellent pain control profile, working peripherally by decreasing the amount of neurotransmitters released from neurons involving noxious stimuli, and also in their central processing. Some of the more common adverse reactions are reparatory depression, sedation, confusion, delirium, nausea, pruritis, constipation, hypotension and bradycardia. Often it is these resulting side effects that extend the length of in hospital rehabilitation, and decrease a patient's overall satisfaction.

Thus we propose the use of a relatively new regional anesthetic technique be employed to further decrease the need for opiates in our prostatectomy patients' post-op course, while adequately controlling their pain.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • prostate cancer for radical prostatectomy

Exclusion criteria

  • chronic pain or opiate use

Treatment and study plan

Transverse Abdominal Plan (TAP)

Procedure

An injectable anesthetic is introduced to a specific anatomic area where the sensory neurons supplying the operative field.

Other names: lidocaine, ropivacaine

standard post op pain control

Procedure

opiates

Other names: timed assessments for pain and medications

Primary outcomes

  1. Total Milligrams of Opiates

    Time frame: 2, 6,12, 24, 48 and 72 hours

    mean number of milligrams used postoperatively

Sponsors and collaborators

Lead sponsor

Nova Scotia Health Authority

Other

Registry information

Official study title

Post Operative Analgesia Using the Transverse Abdominal Plan (TAP) Block in Patients Undergoing a Radical Retropubic Prostatectomy (RRP)

Acronym: TAP

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Jun 3, 2009
Registry last updated
Oct 4, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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