Postoperative Pain After Using a Minimally Invasive Reciprocating Single-file System in Mandibular Molars With Symptomatic Irreversible Pulpitis

The aim of the present study is to assess the incidence and severity of postoperative pain after root canal preparation of mandibular molars with symptomatic irreversible pulpitis using a minimally invasive reciprocating single-file system in comparison to Wave One Gold.

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Key information

Conditions

Root Canal Infection

Age range

19 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients who have vital mandibular molar teeth with irreversible pulpitis without apical periodontitis.
Medically free patients.

Exclusion criteria

Pregnancy or lactation
Patients with para functional habits.
Teeth with non-vital pulps and periapical lesions.
The presence of swelling or a fistulous tract.
Any periodontal pockets with a depth more than 5 mm.
Previous endodontic fillings.
Patients with a history of any systemic diseases.
Severely curved canals and calcified ones.

Treatment and study plan

Reciprocating rotary single-file system

Procedure

One glider will be used then (25/6) will be used to prepare narrow and curved canals as mesials in lower molars, and the large file (45/4) will be used for large canals. Three in-and-out motions were applied with motions until attaining full working length

Wave One Gold rotary file system

Procedure

Wave One Gold glider will be used then primary (25\\7) to prepare narrow and curved canals as mesials in lower molars, and the file (45/5) will be used for large canals. Three in-and-out motions will be applied with motions until attaining full working length

Primary outcomes

Pain assessment

Time frame: after (6) hours, (12) hours, (24) hours, (48) and (72) hours of the procedure

assessment of pain on Visual Analog Scale (VAS) scoring system

Sponsors and collaborators

Lead sponsor

Minia University

Other

Registry information

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Jul 22, 2026
Registry last updated: Jul 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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