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OpenTrials
Completed

NCT Number: NCT06855550

Postoperative Incidence of Atrial Fibrillation Following Cardiac Surgery

Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery. Hypomagnesemia is also likely to be observed in the postoperative period, and several studies have suggested that it could be related to the incidence of postoperative atrial fibrillation. In this study, via a prospective design and adjustment for multiple covariates, the investigators will seek to determine whether plasma magnesium levels are independently associated with the appearance of postoperative atrial fibrillation.

Methods: An analytical design involving a concurrent cohort will be carried out in a high-complexity hospital with a cardiovascular focus. Serial postoperative plasma magnesium measurements will be included as independent variables in a logistic regression model to determine their association with atrial fibrillation after adjusting for multiple covariates.

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Key information

Conditions

Atrial Fibrillation (AF) Arrhythmias, Cardiac Atrial Fibrillation Cardiac Surgery Cardiovascular Diseases Heart Diseases Hypomagnesemia Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Fundación Cardioinfantil-Instituto de Cardiología

Bogotá, Bogota D.C., 110131, Colombia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults in postoperative cardiac surgery

Exclusion criteria

  • Preoperative atrial fibrillation
  • Without complete information regarding plasmatic magnesium postoperative measurements

Treatment and study plan

Primary outcomes

  1. Postoperative Atrial fibrilation

    Time frame: Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first)

    Defined as irregular QRS without p wave during 30 seconds in a 12 derivations EKG.

Secondary outcomes

  1. Mortality

    Time frame: Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first)

    Overall mortality rate.

Sponsors and collaborators

Lead sponsor

Fundación Cardioinfantil Instituto de Cardiología

Other

Registry information

Official study title

Evaluation of Plasmatic Magnesium Levels and Its Association with Atrial Fibrillation After Cardiac Surgery

Important dates

Study start
2015
Primary completion
2016
Study completion
2022
First posted
Mar 4, 2025
Registry last updated
Mar 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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