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Completed

NCT Number: NCT05406843

Postoperative Cognitive Dysfunction in Heart Surgery

To determine the rate of Postoperative Cognitive Dysfunction (POCD) in the early and late postoperative periods by comparing the preop and postop period mini mental status tests in participants undergoing open heart surgery, and to compare the results of the investgators clinic with the world literature.

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Key information

Conditions

Postoperative Cognitive Dysfunction Cognition Disorders Cognitive Dysfunction Confusion Delirium Emergence Delirium Mental Disorders Nervous System Diseases Neurobehavioral Manifestations Neurocognitive Disorders Neurologic Manifestations Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Cognitive Complications Postoperative Complications Signs and Symptoms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Kocaeli Üniversitesi Tıp Fakültesi Hastanesi

Kocaeli, İzmit, 41100, Turkey (Türkiye)

About this study

Postoperative delirium (POD) and Cognitive Dysfunction (POCD) are changes in mental status, especially in the geriatric surgery population.Unlike other forms of delirium, POD results in early full recovery.Postoperative Cognitive Dysfunction (POCD) is more difficult to define and implies temporal consciousness impairment associated with surgery.

While the diagnosis of delirium requires the detection of symptoms, the diagnosis of POCD requires preoperative neuropsychological testing and determining how much reduction will mean cognitive dysfunction. Postoperative delirium management is complex and requires multiple strategies. Methods of treating and preventing POCD are still uncertain.It is known that POCD is most commonly seen in patients undergoing open heart surgery.In this study, the investigators aim is to evaluate whether there is any change in cognitive status in the postoperative period compared to the preoperative period of participants who will undergo open heart surgery due to valve pathology or coronary stenosis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-75 age
  • American Society of Anesthesiologists (ASA) II-III

Exclusion criteria

  • >75 age
  • <18 age
  • Patients who died within 48 hours after the operation

Treatment and study plan

Preoperative cognitive functions of participants undergoing open heart surgery

Other

Surgery times and cross-clamping times of the participants who will undergo open heart surgery were recorded.

Postoperative cognitive functions of particiants undergoing open heart surgery

Other

Changes in mini mental test scores were recorded in the postoperative period.

Primary outcomes

  1. Evaluation of postoperative cognitive functions in participants undergoing open heart surgery.

    Time frame: 1 year

    The aim is to understand whether there is a loss of cognitive functions in the postoperative period, according to the preoperative periods, by testing the participants with open heart surgery on the 3rd day, 7th day, and 2nd month after the surgery.

Secondary outcomes

  1. Comparison with the literature.

    Time frame: 1 year

    Comparison of the results in the investigators clinic with the literature.

Sponsors and collaborators

Lead sponsor

Kocaeli University

Other

Registry information

Official study title

Postoperative Cognitive Dysfunction in Participants Undergoing Open Heart Surgery

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jun 7, 2022
Registry last updated
Jun 9, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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