Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06958029

Postoperative Atrial Fibrillation in Cardiac Surgery

This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in Thailand. The study will examine patient characteristics, surgical factors, and anesthetic management practices that may contribute to the development of this common postoperative complication.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine, Khon Kaen University

Khon Kaen, 40002, Thailand

Location status: Recruiting

Location contact

Sirirat Tribuddharat, MD, PhD

PRINCIPAL_INVESTIGATOR

Thepakorn Sathitkarnmanee, MD

CONTACT

[email protected]

+66819547622

About this study

Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery, with incidence rates reported between 15-30% after valve surgery and 18-74% after coronary artery bypass grafting. POAF typically occurs within 72 hours after surgery and is associated with increased morbidity, mortality, length of hospital stay, and healthcare costs.

The Society of Thoracic Surgeons has identified five major postoperative complications associated with cardiac surgery, including POAF, which can significantly affect patient outcomes. This multicenter observational study will examine the incidence and risk factors of POAF in cardiac surgery patients across three medical centers in Thailand: Srinagarind Hospital at Khon Kaen University, Northeastern Thailand Cardiac Center, and Surat Thani Hospital.

The study will collect data on patient demographics, comorbidities, preoperative laboratory values, perioperative characteristics, surgical procedures (valve surgery, CABG, combined procedures), and postoperative complications. By identifying risk factors associated with POAF, this study aims to develop preventive strategies and improve management protocols for patients at high risk for this complication.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years
  • Patients undergoing cardiac valve surgery or coronary artery bypass grafting (CABG) procedures

Exclusion criteria

  • Patients undergoing aortic surgery
  • Patients undergoing MAZE procedure
  • Incomplete medical records
  • Patients who required mechanical circulatory support before surgery
  • Patients who died during surgery or within 3 days after surgery

Treatment and study plan

cardiac surgery

Procedure

Patients receiving general anesthesia for cardiac surgery

Primary outcomes

  1. Incidence

    Time frame: 72 hours postoperatively

    The incidence of POAF

Secondary outcomes

  1. Risk factors

    Time frame: 72 hours postoperatively

    Risk factors associated with POAF

Study contacts

Contact information is provided by the study sponsor or research team.

Sirirat Tribuddharat, MD, PhD

CONTACT

[email protected]

66-81-6205921

Sponsors and collaborators

Lead sponsor

Khon Kaen University

Other

Registry information

Official study title

Incidence and Risk Factors of Postoperative Atrial Fibrillation in Cardiac Surgery Patients

Acronym: POAF

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 6, 2025
Registry last updated
May 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.