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NCT Number: NCT04110132

Postoperative Analgesia Using Ganglion Impar Block After Anal Surgery

The aim of this study is to evaluate the ganglion Impar block in the prevention of postoperative pain after anal surgery.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Postoperative analgesia using ganglion Impar block after anal surgery

Introduction

Ganglion Impar block may be used for treatment of chronic perineal pain (1) Aim

The aim of this study is to evaluate the ganglion Impar block in the prevention of postoperative pain after anal surgery.

Patients and Methods

After approval of local ethical committee and patient consent, this double blinded randomized study will be done on 60 patients undergoing hemorrhoidectomy surgery in Alexandria University hospital.

After standard general anesthesia with Propofol 1-2mg/kg LMA for airway management and maintenance with Isoflurane 1%. The patient will be randomized into two groups.

Bupivacaine group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Bupivacaine 0.5% 10ml.

Saline group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Normal Saline 10ml Postoperative VAS will be measured each 1 for the first 6 hours then at 9 and 12 hours postoperative.

First request of pain medications will be measured.

Results Results will be collected in tables and graphs. Appropriate statistical analysis will be done.

Discussion Results of the study will be discussed compared to other studies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients undergoing hemorrhoidectomy surgery in Alexandria University hospital.

Exclusion criteria

  • Coagulation effects
  • Allergy to Bupivacaine
  • Previous anal surgery
  • Patient refusal

Treatment and study plan

Ganglion impar block with Bupivacaine.

Procedure

Bupivacaine group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Bupivacaine 0.5% 10ml.

Postoperative VAS will be measured each 1 for the first 6 hours then at 9 and 12 hours postoperative.

Ganglion impar block with normal saline

Procedure

Saline group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Normal Saline 10ml Postoperative VAS will be measured each 1 for the first 6 hours then at 9 and 12 hours postoperative.

Primary outcomes

  1. Postoperative pain

    Time frame: 24 hours

    VAS sore 0-10

Secondary outcomes

  1. First request of pain medications will be measured.

    Time frame: 24 hours

    Time in hours

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammad Hazem I Ahmad Sabry, MD

CONTACT

[email protected]

+201062718827

Sponsors and collaborators

Lead sponsor

University of Alexandria

Other

Registry information

Important dates

Study start
2028
Primary completion
2029
Study completion
2029
First posted
Oct 1, 2019
Registry last updated
Apr 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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