Laparoscopic cholecystectomy
ProcedurePosterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients
NCT Number: NCT06778928
To assess the outcome of posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients in Assuit university hospitals and El Rajhi hospital.
Trial opening soon.
Get Notified18 year–60 year
All sexes
Observational
Cholelithiasis is found in about one third of patients with liver cirrhosis and about twice as much as in the overall population. Predisposing factors for that include functional gallbladder alterations (reduced motility and decreased emptying), reduction in bile acidity, increased unconjugated bilirubin secretion, increased levels of estrogen, and increased intravascular haemolysis due to hypersplenism. Symptomatic biliary stones in patients with liver cirrhosis are associated with higher morbidity and mortality rates than those in patients with a non-cirrhotic liver. laparoscopic cholecystectomy is the gold standard for the treatment of most of gallbladder problems because of its several advantages over open cholecystectomy including shorter convalescence period and hospital stay. Furthermore, considering its safety, it is the gold-standard procedure in selected patients with symptomatic cholelithiasis and hepatic cirrhosis, especially Child-Pugh score A and B patients. Separation of posterior wall of the gallbladder from the liver bed in cirrhotic individuals is difficult and risky during a laparoscopic cholecystectomy surgery because of high-risk gall bladder bed due to fibrosis and tortuous, dilated vessels there so the strategy is leaving the posterior wall intact with the liver and the remnant mucosa was removed either by mucosectomy in patients with acute cholecystitis or by electro fulguration in those with chronic cholecystitis.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients
Time frame: Surgery then 2 days follow up
Time frame: Surgery then 1 week follow up
Time frame: Surgery then 1 week follow up
AST, ALT, Billirubin
Time frame: Surgery then 1 week follow up
Time frame: Surgery then 1 week folow up
Time frame: From the end of induction of anasthesia to the closure of port site incisions
Time frame: surgery then up to 1 week hospital stay before discharge
Contact information is provided by the study sponsor or research team.
Adnan mohamed Mohamed Mohamed salem
CONTACT
Mostafa Mahmoud Mohamed Ibrahim, Lecturer
CONTACT
Assiut University
Other
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