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NCT Number: NCT07531030

Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks for Hip Surgery Analgesia

This study aims to investigate the efficacy of adding a Posterior Pericapsular Deep gluteal block to two other standard nerve blocks-the Pericapsular Nerve Group block and the Lateral Femoral Cutaneous Nerve block-for patients undergoing orthopedic hip surgery. While standard blocks target the front of the hip, many patients still feel pain in the back (posterior) of the joint. Researchers will compare two groups of patients to see if this triple-block combination provides better pain relief and reduces the need for rescue opioid medications in the 24 hours following surgery.

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Key information

Conditions

Postoperative Pain Arthritis Femoral Fractures Fractures, Bone Hip Fractures Hip Injuries Hip Osteoarthritis Joint Diseases Leg Injuries Musculoskeletal Diseases Neurologic Manifestations Osteoarthritis Osteoarthritis, Hip Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Rheumatic Diseases Signs and Symptoms Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain Shams University

Cairo, Abbasia, 11591, Egypt

Location contact

01210366210

CONTACT

Merna H Hilal, MB BCh, MSc

CONTACT

[email protected]

+201142220555

About this study

Patients undergoing elective orthopedic hip surgery will be randomly assigned to one of two groups. Both groups will receive general anesthesia followed by ultrasound-guided nerve blocks. Group 1 will receive a Pericapsular Nerve Group block and a Lateral Femoral Cutaneous Nerve block using 0.25% bupivacaine. Group 2 will receive these same two blocks plus an additional Posterior Pericapsular Deep gluteal block, also using 0.25% bupivacaine.

The primary goal is to evaluate postoperative pain using the Numerical Rating Scale at 6, 12, and 24 hours for both static and dynamic states. Secondary objectives include assessing quadriceps muscle strength using the Lovett Grading Method, measuring total rescue analgesia (nalbuphine) consumption, and monitoring for any complications or differences in length of hospital stay.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age greater than or equal to 18 years.
  • Both genders included.
  • American Society of Anesthesiologists (ASA) physical status classification I-III.
  • Undergoing elective orthopedic hip surgery.
  • Provision of written informed consent.

Exclusion criteria

  • Patient refusal of procedure or participation.
  • American Society of Anesthesiologists (ASA) physical status classification IV.
  • Allergy to any of the drugs used in the study.
  • Local skin infection at the injection site.
  • Coagulation disorder.
  • History of cardiac arrhythmia, seizures, or increased intracranial tension.
  • Alcohol or drug abuse, or psychiatric disease.
  • History of chronic pain.

Treatment and study plan

Posterior Pericapsular Deep Gluteal, Pericapsular Nerve Group, and Lateral Femoral Cutaneous Nerve Blocks.

Procedure

Under ultrasound guidance, patients receive a Pericapsular Nerve Group block, a Lateral Femoral Cutaneous Nerve block, and a Posterior Pericapsular Deep gluteal block. For each of the three blocks, 10-15 ml of 0.25% bupivacaine is injected while observing for adequate fluid spread over the respective anatomical targets.

Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks.

Procedure

Patients receive ultrasound-guided Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve blocks with 10-15 ml of 0.25% bupivacaine for each block.

Primary outcomes

  1. Evaluation of Postoperative analgesic effect through Numerical Rating Scale Pain Score.

    Time frame: 6, 12, and 24 hours postoperatively.

    Evaluation of postoperative analgesic effect through the Numerical Rating Scale for both static and dynamic pain. Static pain is measured after the patient has rested in bed for 15 minutes. Dynamic pain is measured with the hip joint flexed to 45 degrees. The scale ranges from 0 (no pain) to 10 (worst possible pain).

Secondary outcomes

  1. Quadriceps Femoris Muscle Strength.

    Time frame: 1 hour before patient movement.

    Evaluation using the Lovett Grading Method, a manual muscle testing scale from 0 (no contractility) to 5 (complete range of motion against full resistance).

  2. Total Rescue Analgesia Consumption.

    Time frame: First 24 hours postoperatively.

    Total doses of intravenous nalbuphine (in milligrams) administered to the patient.

  3. Length of Hospital Stay.

    Time frame: Approximately 24-72 hours (up to hospital discharge).

    The total number of days from the date of surgery until hospital discharge.

  4. Occurrence of Postoperative Complications.

    Time frame: First 24 hours postoperatively.

    Monitoring for nausea, vomiting, dizziness, or infection/hematoma at the puncture site.

Study contacts

Contact information is provided by the study sponsor or research team.

Hany M El Zahaby, MD

CONTACT

[email protected]

+201227463000

Merna H Hilal, MSc, MB Bch

CONTACT

[email protected]

+201142220555

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Efficacy of Combining Ultrasound-guided Posterior Pericapsular Deep Gluteal Block to Both Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks for Postoperative Analgesia in Orthopedic Hip Surgeries

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 15, 2026
Registry last updated
Apr 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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