Hospital Asociación Para Evitar la Ceguera en México I.A.P.
Mexico City, 04030, Mexico
Location status: Recruiting
NCT Number: NCT07095907
This study aims to evaluate postsurgical functional changes in patients with advanced epiretinal membrane (ERM) (stages 3 and 4) by integrating a controlled macular detachment with a balanced salt solution to the conventional ERM peeling technique.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Mexico City, 04030, Mexico
Location status: Recruiting
The evolution of visual acuity will be analyzed using the ETDRS letter scale. At the same time, anatomical and microvascular changes will be evaluated using optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) to evaluate their impact on visual recovery. This technique is expected to minimize persistent distortion, promote restoration of retinal perfusion, mitigate postoperative ischemia, and improve macular structural stability, potentially leading to more significant functional recovery. It is designed as a prospective longitudinal pilot study; The research will be carried out in the Retina Department of the Association to Prevent Blindness in Mexico (APEC), focusing on patients over 18 years of age with a diagnosis of advanced MRD and eligible for vitreoretinal surgery.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Currently, vitrectomy with epiretinal membrane peeling is the standard procedure; however, its ability to improve visual acuity in these patients remains limited. In this context, controlled macular detachment is emerging as a surgical alternative that could optimize the anatomical and functional restoration of the retina.
Time frame: From the first recruitment evaluation to the last one at 3 months post-surgery
Ability to discriminate fine details at a standard distance, assessed by reading letters on an ETDRS chart.
Time frame: From enrollment to the end of follow-up at the third month.
Central macular thickness measured in microns (µm)
Time frame: From enrollment to the end of follow-up at the third month.
Inner nuclear layer thickness measured in microns (µm)
Time frame: From enrollment to the end of follow-up at the third month.
Presence or absence of disruption of the Ellipsoid layer
Contact information is provided by the study sponsor or research team.
Oriana Gomez Erazo, MD
CONTACT
Raúl Velez Montoya, MD
CONTACT
Asociación para Evitar la Ceguera en México
Other
Post-surgical Functional Results in Patients With Epiretinal Membrane Undergoing Controlled Macular Detachment: Pilot Study.
Acronym: DMER25
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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