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Completed

NCT Number: NCT06182007

Post-Resuscitation Pneumothorax - Analysis of Incidence, Risk Factors and Outcome Relevance

In this retrospective study, the investigators seek to investigate the incidence of pneumothorax following possible risk factors, and elucidate its association with outcomes.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Medical University of Graz

Graz, Styria, 8036, Austria

About this study

This is a retrospective analysis of routine data, collected by a single Emergency Medical System (EMS). Adult patients (≥18 years) hospitalised after Out-of-Hospital Cardiac Arrest (OHCA) who received chest compressions and underwent chest imaging within 12 hours after hospital admission were included.

Variables and outcomes ascertained are built up of the core elements of the latest version of the Utstein Resuscitation Registry Template for OHCA. This includes sex, age, aetiology of arrest, response times of the first emergency medical service team and emergency physician, witnessed cardiac arrest, bystander CPR/AED, arrest location, first monitored rhythm, defibrillation time, drugs given, reperfusion attempted and target temperature management. Additional variables studied were pre-existing health status represented by the Pre Emergency Status Assessment (PESA), history of lung disease, no-flow-time (time from collapse until initiation of CPR), use of a mechanical chest compression device and prehospital CPR duration.

The primary outcome is incidence of pneumothorax, secondary outcomes are survival to hospital discharge and favourable neurological condition at hospital discharge defined by a cerebral performance category (CPC) of 1 or 2.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hospitalized after out of hospital cardiac arrest
  • Chest compressions received
  • Chest imaging within the first 12 hours of admission

Exclusion criteria

  • Traumatic cardiac arrest
  • Chest trauma/surgery/pneumothorax one month prior to cardiac arrest

Treatment and study plan

cardiopulmonary resuscitation

Procedure

Cardiopulmonary Resuscitation (Advanced Life Support) according to current guidelines

Primary outcomes

  1. Presence of pneumothorax

    Time frame: within 12 hours of admission

Secondary outcomes

  1. Survival

    Time frame: to hospital discharge (up to 2 months)

  2. Cerebral Performance Category

    Time frame: at hospital discharge (up to 2 months)

Sponsors and collaborators

Lead sponsor

Auinger, Daniel MD

Other

Registry information

Official study title

Pneumothorax After Cardiopulmonary Resuscitation Following Out-of-Hospital Cardiac Arrest - Analysis of Incidence, Risk Factors and Impact on Outcome

Important dates

Study start
2020
Primary completion
2022
Study completion
2022
First posted
Dec 26, 2023
Registry last updated
Dec 26, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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