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NCT Number: NCT07049380

Post-Operative Analgesic Effect of Tramadol and Nalbuphine in Smoker and Non-Smoker Patients in LC

This study aims to compare pain severity and analgesic requirements between smokers and nonsmokers following laparoscopic cholecystectomy, evaluating the efficacy of two analgesics, tramadol and nalbuphine.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Laparocele

Age range

30 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Allama Iqbal Teaching hospital

Dera Ghazi Khan, Punjab Province, Pakistan

About this study

The primary objectives are to estimate pain severity in smokers versus nonsmokers and identify the effect of tramadol and nalbuphine between these groups.A comparative cross-Sectional design will be employed from Allama Iqbal Teaching Hospital, DG Khan, over four months. Participants will be stratified into subgroups receiving either tramadol or nalbuphine.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Both Male and female patients are included.
  • Adults' patients with Greater than 30 years of age
  • Both Smoker and non-Smokers patients are added (Patients who are chain smoker at least 10 cigarettes per day).

Exclusion criteria

  • Patients are excluded if they have smoking history other than cigarettes smoking like Vapes, Cigar and smokeless tobacco.

Treatment and study plan

Comparative cross sectional

Diagnostic Test

evaluating the efficacy of two analgesics, tramadol and nalbuphine. The primary objectives are to estimate pain severity in smokers versus nonsmokers and identify the effect of tramadol and nalbuphine between these groups

Primary outcomes

  1. Visual Analog Scale (VAS)

    Time frame: 12 Months

    The Visual Analog Scale (VAS) is a tool used to measure pain intensity, mood, or other subjective experiences. It typically involves a 10 cm (100mm) line with descriptive anchors at each end, such as "no pain" and "worst pain imaginable

Sponsors and collaborators

Lead sponsor

Superior University

Other

Registry information

Official study title

Post-Operative Analgesic Effect of Tramadol and Nalbuphine in Smoker and Non-Smoker Patients Following Laparoscopic Cholecystectomy

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jul 3, 2025
Registry last updated
Jul 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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