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OpenTrials
Active, Not Recruiting

NCT Number: NCT07496736

Post-exposure Influenza Prophylaxis in a Hospital Setting

The purpose of this study is to compare the efficacy of 5-day versus 10-day oseltamivir prophylactic treatment in patients who had been exposed to influenza in a hospital setting.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Influenza Infections Influenza, Human Orthomyxoviridae Infections RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

University Medical Centre Ljubljana

Ljubljana, 1000, Slovenia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years or older
  • exposure to influenza during hospitalization
  • risk factors for influenza complications
  • consent for participation obtained

Exclusion criteria

  • younger than 18 years
  • hematological malignancy
  • hospitalized in intensive care unit
  • refusal to participate

Treatment and study plan

oseltamivir

Drug

oseltamivir 5 days

Primary outcomes

  1. frequency of influenza

    Time frame: 10 days after completing prophylaxis

Sponsors and collaborators

Lead sponsor

University Medical Centre Ljubljana

Other

Registry information

Official study title

Post-Exposure Influenza Chemoprophylaxis With Oseltamivir for Five Days vs Ten Days in Acute-Care Hospital: a Non-Inferiority Randomized Open-Label Study

Important dates

Study start
2025
Primary completion
2028
Study completion
2028
First posted
Mar 27, 2026
Registry last updated
Apr 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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