Skip to main content
OpenTrials
Enrolling by Invitation

NCT Number: NCT06500039

Positive Psychological Interventions for Patients With Multiple Sclerosis

This study aims to determine the effectiveness of positive psychological interventions on the quality of life and well-being levels of patients with multiple sclerosis.Two groups will be selected as intervention and control groups. An intervention method consisting of three good things in life and gratitude activities, each lasting two weeks, was determined for the intervention group. An activity was planned for control group participants to write their daily routines.

Enrolling by Invitation

Interested in participating?

Request Info

Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bolu Abant İzzet Baysal University

Bolu, 14300, Turkey (Türkiye)

About this study

People with Multiple Sclerosis (MS) face numerous physical and mental symptoms as well as emotional and social challenges. The fact that the disease usually occurs in young adulthood, when individuals are most productive, causes disability, its unpredictable and variable nature, and the lack of a known treatment make it difficult to live with MS and accept the disease. The physical, cognitive, behavioral and social changes that occur with the disease affect daily life activities, well-being. and greatly affects the quality of life. There are various interventions developed to improve the adaptation processes of individuals diagnosed with a chronic disease such as MS, to prevent and reduce psychiatric symptoms, and to increase quality of life and well-being. One of the intervention approaches is positive psychological interventions from the field of positive psychology. Positive psychological interventions are a psychosocial intervention method based on the systematic completion of certain activities aimed at increasing positive emotions, thoughts and behaviors. Since the interventions focus on strengthening positive mental states rather than reducing psychological symptoms, they also have an advantage over traditional interventions in that they can be applied to both sick and non-patients. However, it appears that positive psychological intervention studies have just begun to be implemented in patients with MS. In our country, no study has been found using positive psychological intervention in MS patients. This study aims to determine the effectiveness of positive psychological interventions on the quality of life and well-being levels of patients with multiple sclerosis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of MS by a neurologist according to McDonald criteria
  • Having at least 1 year of MS history
  • Expanded Disability Status Scale (EDSS) score measured by the neurology clinic is <3.5
  • Being between the ages of 18-65 being literate
  • Ability to communicate in Turkish
  • Volunteering to participate in the study

Exclusion criteria

  • Having an MS attack and using corticosteroid medication for the last 3 months
  • A score of 21 or less on the Montreal Cognitive Assessment (MoCA) test
  • Having a mental or organic disability in communicating
  • Being diagnosed with any chronic disease other than MS
  • Using psychotropic medication or continuing psychotherapy
  • Not having or being able to obtain a phone that can connect to the internet

Treatment and study plan

Positive Psychological Intervention Program

Other

An intervention method consisting of three good things in life and gratitude activities was determined for the intervention group. It will take four weeks. Three good deeds will be held for two weeks, and gratitude activities will be held for the last two weeks. Participants will record the interventions on a prepared booklet.

Writing Daily Routines

Other

An activity was planned for the control group participants to write their daily routines. They will write down their sleep, nutrition, hygiene and shopping routines, which will be different each week for four weeks. Control group participants will also be given a booklet to write on.

Primary outcomes

  1. Multiple Sclerosis Quality of Life Scale (MSQOL)-54

    Time frame: six month

    It was developed by Vickrey, Hays, Harooni, Myers, and Ellison (1995). The scale consists of 2 main groups, composite physical health (BFS) and composite mental health (BMS), 12 subgroups and 2 independent items. The reliability coefficients of the scale were found to be between 0.75-0.96, and the test-retest reliability coefficients were found to be between 0.66-0.96. BFS and BMS scores, the two main groups of the MSQOL-54 scale, take a value between 0-100. A high score from the scale indicates a high quality of life.

  2. PERMA Measuring Tool

    Time frame: six month

    It was developed by Butler and Kern (2016) to measure well-being levels. The scale consists of a total of 23 items, 15 items measuring the components of the well-being model and 8 filler items. Among the filler items in the scale, items 7, 12, 14 and 20 are reverse coded. There are 3 items in each dimension of the scale, which consists of 15 items. Sub-dimension scores are calculated by taking the average of the 3 items in the relevant sub-dimension. The Cronbach Alpha internal consistency coefficient for the total score of the scale is 91.

Secondary outcomes

  1. Positive and Negative Mood Scale (PNDS)

    Time frame: six month

    The Positive and Negative Affect Scale was developed by Watson and colleagues (1988) to assess positive and negative emotion. There are a total of 20 items in the scale, 10 items for each subscale. The scale is a five-point Likert scale ranging from 1 (very little to not at all) to 5 (very much). The score a person gets from the positive or negative emotion subscales varies between 10 and 50. The internal consistency coefficients of the original form of the scale are .88 for positive emotion and .85 for negative emotion.

Sponsors and collaborators

Lead sponsor

Abant Izzet Baysal University

Other

Registry information

Official study title

The Effect of Positive Psychological Interventions on Quality of Life and Well-Being in Patients With Multiple Sclerosis

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Jul 15, 2024
Registry last updated
Aug 22, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.