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NCT Number: NCT06388109

Positive Peers Intervention Clinical Trial

The goal of this clinical trial is to learn if the Positive Peers mobile app intervention increases rates of viral suppression in young (13-34 y/o) persons with HIV.

Does use of the Positive Peers app improve viral suppression among young minority persons with HIV? What user characteristics are associated with a) viral suppression, b) retention in care, and c) perceived HIV-related stigma?

Participants will:

* download the mobile app onto their personal smartphone * Use the mobile app as they find useful * complete online surveys at enrollment, 3 mo, 6, mo, 9 mo and 12 months.

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Key information

Conditions

HIV Infections Blood-Borne Infections Communicable Diseases Genital Diseases Immune System Diseases Immunologic Deficiency Syndromes Infections Lentivirus Infections RNA Virus Infections Retroviridae Infections Sexually Transmitted Diseases Sexually Transmitted Diseases, Viral Urogenital Diseases Virus Diseases

Age range

13 year–34 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Northeast Valley Health Corporation, Van Nuys, California, United States

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About this study

Participants will load the Positive Peers app on their personal device (either immediately or after a 6 month delay) and be encouraged to use the app regularly. Eligible patients who decline participation in the intervention will be asked to participate in an observational arm.

All participants will complete a brief baseline survey. Participants in the immediate or delayed arms will also complete surveys at 3, 6, 9, and 12 months. Medical data will be collected from the medical record and usage data will be collected from the app itself. Medical data will be collected for 12 months prior to enrollment and 18 months after enrollment. At the end of the study, participants are welcome to continue to use the app.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • HIV+
  • Identifies as either a racial, ethnic, sexual or gender minority

One of the following:

  • Newly diagnosed within last 12 months
  • Out of care (greater than 6 months between any two HIV provider visits in last 24 months)
  • Not virally suppressed (any viral load > 200 copies in last 24 months)
  • Has a working smartphone
  • Functional English ability

Exclusion criteria

  • prior use of Positive Peers mobile app

Treatment and study plan

Positive Peers mobile app

Other

Positive Peers is a multifunctional mobile app using a mind, body, spirit theme aimed to improve HIV care outcomes.

Primary outcomes

  1. Viral suppression

    Time frame: 6 months

    Proportion of participants who have HIV viral load <200 copies/ ml

Secondary outcomes

  1. Correlates of app use and viral suppression

    Time frame: 6 months

    Identify participant demographic and psychosocial factors from the baseline survey that correlate with app use and viral suppression (viral load < 200 copies/ ml).

  2. Correlates of app use and retention in care

    Time frame: 12 months

    Identify participant demographic and psychosocial factors from the baseline survey that correlate with app use on retention in care (completing office visit at least every 6 months)

  3. Correlates of app use and HIV related perceived stigma

    Time frame: 3 months

    Identify participant demographic and psychosocial factors from the baseline survey that correlate with app use and changes in HIV-related perceived stigma on the HIV Stigma scale (Eriksson).

Study contacts

Contact information is provided by the study sponsor or research team.

Ann Avery, MD

CONTACT

[email protected]

Jennifer McMillen-Smith, LISW-S

CONTACT

[email protected]

2167784051

Sponsors and collaborators

Lead sponsor

MetroHealth Medical Center

Other

Collaborators

  • Kent State University

Registry information

Official study title

Randomized Control Trial of Positive Peers mHealth App as a Clinic-based Intervention to Optimize HIV Outcomes Among Young, Minority Persons Living With HIV

Acronym: PoPIT

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Apr 29, 2024
Registry last updated
Oct 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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