The Burn Centre at Linköping University Hospital,
Linköping, 58185, Sweden
NCT Number: NCT04412759
The purpose of this study was to compare two wound dressing products for partial thickness burns in adults.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Linköping, 58185, Sweden
After being informed about the study, all patients that had given written informed consent underwent screening. If eligible study participants were randomized to be treated wih either the standard dressing of care; pigskin or a microbial cellulose. Dressing were applied within 72 hours after burn injury. Evaluation was done in an open manner due to the specific characteristics of the dressings. Study particpants were followed weekly until complete wound closure and after that evaluated at 6 and 12 months after injruy for burn scar outcome.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
polymer dressing synthesized in abundance with Acetobacter Xylinum
Time frame: Evaluated at each visit (1-3 times per week) from admission until complete healing, up to 6 months
Healing time was calculated from the date of injury to the date when the wound bed was assessed as completely (100 %) re-epithelialized, with no need for further dressing changes other than protection against shearing according to the treating physician.
Time frame: Evaluated at each visit (1-3 times per week) from admission until complete healing, up to 6 months
Wound infections were diagnosed (by the burn surgeon) if they fulfilled at least two of the following criteria:
(based on the American Burn Association definition of burn wound infection)
Time frame: Evaluated at each visit (1-3 times per week) from admission until complete healing, up to 6 months
The patients were asked to estimate the burn wound pain at rest, during activity, and during dressing changes using a numerical rating scale (NRS) where 0 indicated no pain and 10 the worst pain ever imaginable.
Time frame: From admission until discharge, up to 6 months
All patients hospitalized for their burns were monitored by the study nurse and the day of discharge was noted in the CRF. Any readmission after initial discharge was also noted and included in the total length of stay.
Time frame: Evaluated at six and 12 months after injury
Burn scar outcome was evaluated using the Patient Observer Scar Assessment Scale (POSAS). The scale includes two separate subscales, The Observer Sscale, used by an experienced burn occupational therapist and the Patient Sscale, used by the study participants.
University Hospital, Linkoeping
Other
PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS - A RANDOMISED CLINICAL TRIAL
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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