Population Study of the Prevalence of Celiac Disease and Other Gluten-dependent Disorders in Children and Adolescents

The purpose of this screening program is to identify people at high risk for developing celiac disease, which is due to the genetic intolerance of gluten - a protein found in wheat, rye and barley. When a person with celiac disease consumes gluten-containing foods, his immune system damages the mucous membrane of the small intestine. Inflammation develops and, as a result, the absorption of vitamins, minerals and other vital nutrients is disrupted. Studies have shown that timely diagnosis of celiac disease is important for the treatment or prevention of its complications. Left untreated, the disease can lead to impaired growth and development, diabetes, cancer, or other diseases. In Europe and the USA, celiac disease is a chronic disease that occurs in approximately one in 100 and one in 22 who have risk factors. There are frequent cases of an erased or low-symptom course of celiac disease. Unfortunately, ninety-seven percent of cases remain undiagnosed and, accordingly, do not receive proper treatment. A screening program will increase knowledge about the disease and contribute to the early detection of the disease.

Inclusion criteria

• Schoolchildren from various districts of Moscow selected as a result of questioning in the risk group for the development of celiac disease
• Availability of written informed consent of the child over 14 years of age to participate in the study;
• Availability of written informed consent of the parent of the child to participate in the study;
• Age from 7 to 18 years;
• Male and female gender;
• The number of points according to the results of the survey is more than 25.

Exclusion criteria

• Age up to 7 years and over 18 years.
• The lack of written informed consent of the child over 14 years of age to participate in the study;
• The lack of written informed consent of the parent / guardian of the child to participate in the study;
• The number of points on the results of the survey from 0 to 24