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NCT Number: NCT07290296

Popliteus Muscle Release Versus Kinesio Taping

The aim of the current study is to compare the effect of popliteus muscle release and Kinesio taping on pain intensity, function, dynamic balance, and quadriceps muscle strength in patients with patellofemoral pain syndrome.

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Key information

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo

Cairo, Egypt

Location status: Recruiting

About this study

Patellofemoral pain syndrome has been described as one of the most perplexing and clinically challenging chronic disorders.

Symptoms usually include diffuse pain originating from the anterior aspect of the patella and commonly along the medial aspect of the knee. It therefore limits daily activities that need loading on a flexed knee. There is a high incidence, especially among runners, with patellofemoral pain syndrome accounting for 46% of running-related injuries. However, the etiology of this disorder remains vague and controversial. This is reflected in the lack of consensus on how patellofemoral pain syndrome should be treated clinically. Patellofemoral pain syndrome participants have demonstrated abnormal gait patterns with decreased stance phase knee flexion, decreased walking velocity, and decreased muscle activity of the quadriceps musculature. Restoration of normal gait kinematics may be an important component of improving function.

The soft tissue manipulation decreased knee pain and improved muscle activity. Therefore, incorporating popliteus manipulation can be effective in the treatment of anterior knee pain.

Several systematic reviews and meta-analyses of Kinesio Taping treatment in different knee or musculoskeletal problems have been published in recent years. The support taping could reduce pain as an adjunct to traditional exercise therapy in patients with patellofemoral pain syndrome.

Kinesio Taping has a significant effect on pain reduction, motor function improvement, and muscle activity change.

So, the current study will help to determine the effect of myofascial release and Kinesio Taping of the popliteus muscle on patellofemoral pain syndrome.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients of both genders with an age range of 18-30 years old.
  • minimum 3-month history of patellofemoral pain.
  • a pain score for worst pain intensity during the previous week of 3 or more on a Visual Analog Scale (0-10, most pain).
  • reproduced by at least two of the following activities: Stair ascent or descent, hopping, running, prolonged sitting, squatting, or kneeling and present on at least one of the following clinical tests: Compression of the patella or palpation of the patellar facets.

Exclusion criteria

  • Clinical, x-ray, or MRI findings indicative of other specific pathology, including osteoarthritis, meniscal, ligament, or cartilage injury, or apophysitis.
  • recurrent patellar subluxation or dislocation.
  • cortisone use over an extended period of time.
  • previous surgery to the knee joint; trauma to the knee joint affecting the presenting clinical condition.
  • physiotherapy or other similar exercises for patellofemoral pain syndrome within the previous 3 months.

Treatment and study plan

traditional physical therapy treatment

Other

Quadriceps strength, hip abduction strength, hip extension strength, hamstring stretch, gait training

Popliteus Muscle Release

Other

Myofascial release for the popliteus muscle

Kinesio Taping

Other

Kinesio tape on the popliteus muscle

Primary outcomes

  1. Pain intensity

    Time frame: It will be assessed at baseline and after 4 weeks.

    by visual analogue scale The visual analogue scale represents the pain range that a patient thinks they might experience. The line is typically 10 centimeters long, with anchor descriptors such as (in the pain context) "no pain" and "worst pain imaginable." The patient makes a mark reflecting his or her perception, and the distance from the left endpoint to the mark is measured in centimeters. Higher scores represent worse pain.

  2. Knee Function

    Time frame: It will be assessed at baseline and after 4 weeks.

    by kujala scale The Arabic Kujala Patellofemoral Disorder scale, also called the anterior knee pain scale, is composed of 13 multiple-choice questions, each contributing to a total score ranging from 0 to 100. A higher score indicates better knee function and less pain, while a lower score reflects greater pain and disability.

  3. Balance

    Time frame: It will be assessed at baseline and after 4 weeks.

    by Star Excursion Balance Test (SEBT)

Secondary outcomes

  1. Quadriceps Strength

    Time frame: It will be assessed at baseline and after 4 weeks.

    by handheld dynamometer

Study contacts

Contact information is provided by the study sponsor or research team.

Hafsa He Abdullah, MSc

CONTACT

[email protected]

01007069080

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Popliteus Muscle Release Versus Kinesio Taping on Patellofemoral Pain Syndrome

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Dec 18, 2025
Registry last updated
May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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