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NCT Number: NCT03423420

Pontos-Central Venous Pressure and Cardiac Surgery

Recent studies indicated the central venous pressure (CVP) as a prognostic marker. Therefore, we retrospectively analyzed the CVP on admission to the intensive care unit (ICU) in cardiac surgery patients regarding its prognostic value for morbidity and mortality.

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Key information

Conditions

Central Venous Pressure

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Charité - Universitaetsmedizin Berlin

Berlin, 10117, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • In-patients of the Charité Universitätsmedizin Berlin
  • at least 18 years old
  • female or male sex
  • cardiosurgical intervention (OPS 5.35 and 5.36) between 01/06 and 12/13.
  • post-operative monitoring of anesthesiological intensive care unit

Exclusion criteria

  • previous cardiosurgical interventions during the same hospital stay.
  • incomplete documentation

Treatment and study plan

Primary outcomes

  1. mortality

    Time frame: an average of 30 days

    In-Hospital mortality

Secondary outcomes

  1. Central venous pressure

    Time frame: intensive care unit stay, an average of 5 days

    central venous pressure on intensive care unit

  2. Hospital stay

    Time frame: an average of 13 days

    Length of hospital stay

  3. ICU stay

    Time frame: an average of 5 days

    Intensive care unit length of stay

  4. ICU readmission

    Time frame: an average of 30 days

    Amount of hospital readmissions

  5. Renal insufficiency - 1

    Time frame: intensive care unit stay, an average of 5 days

    Incidence of renal insufficiency

  6. Renal insufficiency - 2

    Time frame: intensive care unit stay, an average of 5 days

    dialysis duration

  7. Renal insufficiency - 3

    Time frame: intensive care unit stay, an average of 5 days

    Urine production

  8. Stroke

    Time frame: hospital length of stay, an average of 13 days

    incidence of strokes

  9. mortality rate-1

    Time frame: 90 days

    mortality rate after 90 days

  10. mortality rate-2

    Time frame: 180 days

    mortality rate after 180 days

  11. mortality rate-3

    Time frame: 3 years

    mortality rate after 3 years

  12. mortality rate-4

    Time frame: 1 year

    mortality rate after 1 year

  13. mortality rate-5

    Time frame: 5 years

    mortality rate after 5 years

Other outcomes

  1. priority of surgery

    Time frame: an average of 1 day

    priority of surgery selected from a three point categorial scale with the categories elective, urgent and emergency

  2. type of surgery

    Time frame: an average of 1 day

    type of surgery selected from the three point categorial scale with categories bypass graft, valve replacement or combination of both

  3. duration

    Time frame: an average of 4 hours

    duration of surgery

  4. APACHE II

    Time frame: an average of 30 days

    APACHE II Score of patients on admission on the ICU

  5. ACEF Score

    Time frame: an average of 1 day

    preoperative ACEF Score of patients undergoing surgery

Sponsors and collaborators

Lead sponsor

Charite University, Berlin, Germany

Other

Registry information

Official study title

High Central Venous Pressure After Cardiac Surgery is Associated With Increased Morbidity and Mortality

Important dates

Study start
2006
Primary completion
2013
Study completion
2013
First posted
Feb 6, 2018
Registry last updated
Jul 25, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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