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Completed

NCT Number: NCT02298621

Pomegranate Juice and Metabolic Syndrome

The effect of pomegranate juice (PJ) intake on cardiovascular risks in subject with metabolic syndrome.

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Urmia University of Medical Sciences

Urmia, +98, Iran

About this study

The effect of pomegranate juice (PJ) intake on cardiovascular risks in subject with metabolic syndrome in shabestar.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • presence of ≥3 of the following diagnostic of MetS:
  • serum TGs of at least 150 mg/dL,
  • waist circumference of more than 102 cm (40 in) in men and more than 88 cm (35 in) in women,
  • high-density lipoprotein (HDL) level less than 40 mg/dL in men and less than 50 mg/dL in women,
  • blood pressure 135/85 mm Hg or higher, or
  • fasting glucose 100 mg/dL or Higher

Exclusion criteria

  • liver cirrhosis,
  • chronic pancreatitis,
  • gastrointestinal or connective diseases,
  • kidney stones, or
  • renal failure,
  • alcohol Consumption,
  • having an allergy to pomegranate juice,
  • a change in diet,
  • the large increase in LDL so that required drug treatment.
  • use of statins of fibrates, corticosteroids, nitrates, acetyl-salicylic acid or other anti-platelet drugs, oral hypoglycemic drugs, nonsteroidal anti-inflammatory drugs, or drugs interfering with coagulation;
  • pregnancy or lactation in the past 6 mo, supplementation with vitamins or antioxidants

Treatment and study plan

pomegranate juice

Other

Randomized clinical trial or RCT

Placebo

Other

Randomized clinical trial or RCT

Primary outcomes

  1. Change from baseline in values of metabolic syndrome components at 1 week

    Time frame: 1 week

Secondary outcomes

  1. Change from baseline in values of insulin resistance (HOMA-IR), total cholesterol, LDL-C, VLDL-C and hs-CRP at 1 week

    Time frame: 1 weeks

    Insulin resistance via HOMA-IR

Sponsors and collaborators

Lead sponsor

Urmia University of Medical Sciences

Other

Registry information

Official study title

The Effect of Pomegranate Juice Intake on Cardiometabolic Factors in Subjects With Metabolic Syndrome.

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Nov 24, 2014
Registry last updated
Nov 24, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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