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OpenTrials
Completed

NCT Number: NCT07627555

Polyunsaturated Fatty Acids-based Bars Effect on Metabolic Syndrome Patients

This study aimed to manage dyslipidemia through Polyunsaturated fatty acids based bar among patients with metabolic syndrome.

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Key information

Age range

40 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Lahore

Lahore, Pakistan

About this study

This study was conducted at Chaudhry Muhammad Akram Teaching & Research Hospital, Lahore. Total 60 individuals diagnosed with metabolic syndrome, like deranged lipid profile, high blood pressure (ranges mild to moderate), and elevated levels of HbA1c (5.6%-6.4%), aged between 40 to 65 years were part of the study. The participants were randomly selected and divided into two groups.

Control group (T 0 ) was given one jelly candy as mid-morning snack. The experimental group (T 1 ) was given PUFA bar one each daily The follow-up for patients has been conducted monthly, all laboratory test (blood pressure, lipid profile, HbA1c and CRP) has been done on 1st and after 8 weeks. The baseline and post-test study data is compared to test the study hypothesis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Metabolic syndrome patient's age 40 to 65 years with BMI (above 25 kg/m 2 ) was major part of this study.
  • Patients having Triglyceride levels range from mild to moderate (150 to 499 mg/dL) are included in the study.
  • Patients having LDL (Low density lipoprotein) range from mild (130-159 mg/dL) to moderate (160-189 mg/dL) are included in the study.
  • Patients having HDL (High-density lipoprotein) range from mild to moderate (60 mg/dL or higher) have been included in the study.

Exclusion criteria

  • Lactating and pregnant women will not be included.
  • Patients who are using any kind of medicine.
  • Any person allergic to nuts.
  • Adults suffering from critical health conditions, including cancer.

Treatment and study plan

Jelly Candy

Dietary Supplement

participants were advised to take one jelly candy as a mid-morning snack for a duration of 2 months.

PUFA Bar

Dietary Supplement

Participants were advised to taken one PUFA bar as a mid- morning snack for a duration of 2 months.

Primary outcomes

  1. Body Mass Index

    Time frame: 60 days

    BMI is defined as body weight in kilograms divided by height in meters squared (kg/m²). BMI cut-off points are used to assess weight status, categorizing individuals as underweight, normal, overweight or obese. Obesity is further classified into grades 1, 2 and 3.

  2. Lipid Profile

    Time frame: 60 days

    Total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides levels were measured.

Sponsors and collaborators

Lead sponsor

University of Lahore

Other

Registry information

Official study title

Effects of Polyunsaturated Fatty Acids-based Bars on Lipid Profile Among Patients With Metabolic Syndrome

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 4, 2026
Registry last updated
Jun 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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