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Completed

NCT Number: NCT07047833

Plyometric Training With or Without Hamstring Strengthening for Preventing ACL Injuries in Female Amateur Athletes

This randomized controlled trial explored the effect of plyometric training with or without hamstring strengthening in preventing anterior cruciate ligament (ACL) injuries among female amateur athletes aged 18 to 30. Sixty participants were divided equally into two groups: one received plyometric training combined with hamstring strengthening, and the other received plyometric training only. Both groups trained twice per week over a six-week period. Outcomes measured included knee strength (flexion and extension), dynamic balance (Star Excursion Test), and functional mobility (KOOS).

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Key information

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

The University of Lahore Teaching Hospital

Lahore, 54590, Pakistan

About this study

This study examined whether combining hamstring strengthening with plyometric training provides greater benefits in preventing anterior cruciate ligament (ACL) injuries than plyometric training alone among female amateur athletes. Conducted as a randomized controlled trial, the research involved 60 participants aged 18 to 30, randomly assigned to two equal groups. Group A underwent a six-week intervention involving both plyometric and hamstring strengthening exercises, while Group B participated in plyometric training only. Each group trained twice weekly, and the outcomes were measured at baseline, Week 3, and Week 6 using a handheld dynamometer for knee strength (flexion and extension), the Star Excursion Balance Test (SET) for dynamic balance, and the Knee Injury and Osteoarthritis Outcome Score (KOOS) for functional mobility.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female amateur athletes between the ages of 18-30 years old.
  • Participating in sports that involve jumping, cutting and pivoting movements (e.g. basketball, soccer).
  • On average, athletes exercised between six and eight times per week including competition.
  • Able to perform basic jumping and landing mechanics safely.

Exclusion criteria

  • Recreational athlete or untrained individual
  • Athletes with less than five training sessions per week.
  • Athletes who were operated with techniques other than the bone patellar-tendon, bone graft (BPTB), or who were operated by different surgeons and rehabilitated by several physical therapist.
  • Athletes with a history of muscle or joint injuries.
  • Athletes who had already followed a pre-operative rehabilitation program.

Treatment and study plan

Plyometric Training with Hamstring Strengthening

Behavioral

This intervention consisted of a six-week training protocol involving both plyometric exercises and targeted hamstring strengthening. Sessions were conducted twice per week, lasting 60 minutes each. Plyometric drills included squat jumps, depth jumps, and lateral jumps, while hamstring exercises included Nordic hamstring curls and machine-based leg curls. All sessions included a standardized 15-minute warm-up and a 5-minute cool-down. The program was designed to enhance lower limb strength, balance, and neuromuscular control for ACL injury prevention in female amateur athletes.

Plyometric Training Only

Behavioral

This intervention involved a six-week plyometric-only training program delivered twice weekly for 40-minute sessions. Exercises included squat jumps, depth jumps, and lateral jumps, performed with progressive intensity and control. Each session included a standardized 15-minute warm-up and a 5-minute cool-down. The program aimed to improve lower limb power, balance, and functional mobility to reduce the risk of ACL injuries in female amateur athletes.

Primary outcomes

  1. Knee Flexion and Extension Strength (Measured Using Handheld Dynamometer)

    Time frame: Baseline, Week 3, and Week 6

    Lower limb strength was assessed through a handheld dynamometer measuring knee flexion and extension in kilograms. This tool has high reliability for assessing muscle strength and functional performance in athletic populations. Measurements were taken at baseline, Week 3, and Week 6 to evaluate changes over time due to the training interventions.

Secondary outcomes

  1. Dynamic Balance (Assessed Using Star Excursion Balance Test - SEBT)

    Time frame: Baseline, Week 3, and Week 6

    The SEBT evaluates dynamic postural control and balance by measuring reach distance in multiple directions while maintaining single-leg stance. It is a validated predictor of lower extremity injury risk and is used to track neuromuscular improvements in response to training. Performance was recorded at three intervals during the study.

  2. Functional Mobility (Assessed Using KOOS - Knee Injury and Osteoarthritis Outcome Score)

    Time frame: Baseline, Week 3, and Week 6

    The KOOS is a patient-reported outcome tool consisting of 5 subscales: Pain, Symptoms, ADL, Sport/Rec, and Quality of Life. It assesses functional limitations and knee-related quality of life. Scores range from 0 (severe problems) to 100 (no problems). It was used to monitor improvements in knee function due to training.

Sponsors and collaborators

Lead sponsor

University of Lahore

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 2, 2025
Registry last updated
Jul 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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