Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.

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Key information

Conditions

Postoperative Bleeding Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Postoperative Hemorrhage

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Anesthesiology and Intensive Care Medicine, Medical University Graz

Graz, 8036, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

intake of Clopidogrel, Prasugrel, or Ticagrelor within the last 7 days
spontaneous bleeding or impeding surgery (major vascular surgery, intraperitoneal or intrathoracic surgery, ENT-surgery, orthopedic or trauma surgery, prostatic surgery)

Exclusion criteria

concomitant medication with warfarin
renal insufficiency needing dialysis
concomitant therapy with GPIIB/IIIA Antagonists
expected duration of operation >30min

Treatment and study plan

Primary outcomes

increased risk of bleeding (according to TIMI definition)

Time frame: 24hours postoperatively

Sponsors and collaborators

Lead sponsor

Medical University of Graz

Other

Registry information

Official study title

Does Platelet Inhibition Predict Surgery Related Bleeding in Patients Undergoing Non-Cardiac Surgery During Dual Antiplatelet Therapy

Acronym: BIANCA

Important dates

Study start: 2010
Primary completion: 2014
Study completion: 2014
First posted: May 28, 2012
Registry last updated: Oct 23, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed