Plasma Triglyceride Extraction by The Muscle

Inclusion criteria

• Body mass index (BMI): < 25 kg/m2 or > 30 kg/m2;
• Insulin sensitivity index (ISI): insulin-sensitive ISI ≥ 7, insulin-resistant ISI ≤ 5.

Exclusion criteria

• Medication or supplements known to affect either endothelial function or lipid metabolism (i.e. arginine, protein, fish oil)
• Acute illness
• Uncontrolled metabolic disease, including liver or renal disease
• Atrial fibrillation, history of syncope, limiting or unstable angina, congestive heart failure, known or suspected right-to-left, bi-directional or transient right-to-left cardiac shunts
• Cardiac pacemaker or other medical device implanted in the body
• Pulmonary hypertension or other unstable cardiopulmonary conditions
• ECG documented abnormalities or valvular disease
• Low hemoglobin or hematocrit (i.e., lower than accepted laboratory values)
• History of hypertension or elevated blood pressure (systolic, >140 mmHg or a diastolic, >95 mmHg)
• History of hyperlipidemia or plasma triglyceride concentration >200 mg/dl
• Diagnosed diabetes, or 2-h plasma glucose >200 mg/dl during an oral glucose tolerance test
• Current participation in a weight-loss regimen, including extreme dietary practices
• Use of anabolic steroids or corticosteroids (within 3 months)