Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation

Inclusion criteria

• Age between 18 and 70 years old (the age limit can be relaxed if the patient has good organ function and a good neurological prognosis after evaluation).
• The cardiac arrest is witnessed, and bystanders perform traditional cardiopulmonary resuscitation (CPR), and the time interval from the occurrence of cardiac arrest to the start of traditional CPR is no more than 5 minutes.
• The causes of cardiac arrest are reversible, such as cardiogenic, pulmonary embolism, severe hypothermia, drug poisoning, trauma, acute respiratory distress syndrome, etc.
• After 20 minutes of traditional CPR, there is no restoration of spontaneous circulation or hemodynamic instability, or the restoration of spontaneous circulation occurs, but the spontaneous heart rhythm cannot be maintained.
• The informed consent has been signed.

Exclusion criteria

• Infectious diseases, such as hepatitis B, hepatitis C, AIDS, syphilis, etc.
• Hematological diseases, such as hematological malignancies, aplastic anemia, idiopathic thrombocytopenic purpura (ITP), etc.
• Malignant tumors in other systems except the hematological system.
• Patients who have received massive plasma or platelet transfusions during hospitalization or recently.