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NCT Number: NCT07563400

Plaque Removal in Children Using Charcoal and Nylon Toothbrushes

This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush. We want to see which toothbrush is better at removing plaque and reducing bacteria in the mouth. Children will be randomly assigned to use one of the toothbrushes. We will measure the levels of bacteria in small samples of fluid taken from the gums to see if one toothbrush reduces harmful bacteria more than the other.

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Key information

Age range

6 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This study is a clinical trial designed to compare the effectiveness of two types of toothbrushes in children aged 6-10. One group of children will use a toothbrush with charcoal-infused bristles, while the other group will use a standard nylon bristle toothbrush. All children will be taught the same brushing technique and will brush their teeth twice daily for two minutes using a pea-sized amount of toothpaste.The study will last two weeks. Researchers will measure four times how much dental plaque is removed from each child's teeth, collect samples from the gums to examine bacteria, and test the toothbrush bristles for bacterial contamination by counting bacterial colonies.The goal is to determine which toothbrush is better at cleaning teeth and reducing harmful bacteria in the mouth.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ● Children aged 6 to 10 years.
  • Medically free patients with no physical disability.
  • Patients must have proper oral hygiene.
  • Cooperative patients who will comply with follow-ups.
  • Parents who accept to sign informed consent.

Exclusion criteria

  • ● Children with a medical condition or physical disability,
  • Children undergoing antibiotic treatment
  • Children with crowding, fixed or removable orthodontic appliances.
  • Children with pre-shedding mobile teeth were excluded from study.
  • Children who will be unable to attend follow-up visits.
  • Parents refuse to give written formed consent.
  • Presence of painful teeth.
  • Presence of active carious lesions

Treatment and study plan

soft charcoal infused bristle toothbrush (iLive) with bamboo handle

Device

manual toothbrush with soft charcoal infused bristles designed fordaily oral hygiene measures. Participants will be instructed to brush twice daily for two minutes using herbal toothpaste

soft nylon bristle toothbrush (Oral B JUNIOR 6-12)

Device

Manual toothbrush with soft nylon bristles designed for daily oral hygiene measures. Participants will be instructed to brush twice daily for two minutes using herbal toothpaste

Primary outcomes

  1. Change in full-mouth plaque score assessed by O'Leary Plaque Control Index from baseline to 2 weeks

    Time frame: aseline, immediately after training, 1 week, and 2 weeks post-training

    Full-mouth plaque score will be measured using the O'Leary Plaque Control Index at four time points: baseline (before training), immediately after training, one week, and two weeks post-training. Each tooth surface (mesial, distal, buccal, and lingual) will be examined. The plaque score will be expressed as the percentage of plaque-containing surfaces relative to the total number of surfaces examined

Study contacts

Contact information is provided by the study sponsor or research team.

Mennatullah Y Abou El Enein

CONTACT

[email protected]

+201111184215

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Efficacy of Plaque Removal and Antibacterial Properties of Charcoal Infused Bristle Vs Nylon Bristle Toothbrushes in Children: A Randomized Clinical Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 4, 2026
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.