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Completed

NCT Number: NCT03614312

Placenta Development Study

This study will help us learn more about how the placenta develops.

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Key information

Conditions

Healthy

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Arkansas Children's Nutrition Center

Little Rock, Arkansas, 72202, United States

About this study

The primary purpose of this study is to understand the epigenetic signaling events in placental trophoblast development.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI - 18-25 kg/m2
  • at least 18 years of age
  • singleton pregnancy
  • less than 36 weeks and plan to deliver in the Little Rock/North Little Rock Area

Exclusion criteria

  • Women with pre-existing medical conditions (e.g. diabetes, hypertension, pre-eclampsia, STD, gestational diabetes)
  • Women who are using recreational drugs, tobacco, or alcohol during their pregnancy.
  • Women who plan on keeping their placenta following delivery for non-medical reasons.

Treatment and study plan

Primary outcomes

  1. Number of participants that placental syncytial fusion involves epigenetic changes in histone modifications

    Time frame: 40 weeks

    Number of participants that histone acetyltransferases eszymes, CBP and p300 affect syncytial fusion

Sponsors and collaborators

Lead sponsor

Arkansas Children's Hospital Research Institute

Other

Registry information

Official study title

Epigenetic Mechanisms Underlying Trophoblast Syncytialization

Important dates

Study start
2018
Primary completion
2021
Study completion
2021
First posted
Aug 3, 2018
Registry last updated
Dec 20, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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