Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07703852

Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected Pneumonia

Pneumonia is a common pathology with significant morbidity and mortality. It is recommended in his diagnostic approach to perform either a chest X-ray or a pleuropulmonary ultrasound. Previous studies have shown the advantages of ultrasound in terms of diagnostic performance cost and patient irradiation. However, it remains little used in clinical practice.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The study will be conducted in the Emergency Department of grenoble University Hospital.

Patient admitted to the emergency department for respiratory symptoms (cough, fever, and/or dyspnea) will be enrolled in the study according to the inclusion and non-inclusion criteria and after obtaining his consent.

The investigator will perform the pleuropulmonary ultrasound following the clinical examination carried out by the physician in charge of the patient.

The patient's care is unaffected by the pleuropulmonary ultrasound's outcome, which is unknown to the physician in charge of the patient.

Data collection after the patient's discharge from the emergency department.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient over 18 years admitted the the emergency department of Grenoble Alpes University Hospital with respiratory symptoms (cough and/or dyspnea, fever).
  • No objection by the subject to the study
  • Affiliated to the french social security system (or equivalent)

Exclusion criteria

  • Patient admitted to a life-threatening emergency
  • Patient already on antibiotic therapy on admission
  • Patient excluded from another study
  • Patient with respiratory signs following chest trauma
  • Unable to communicate or non-french speaking patients or those with impaired comprehension or consciousness
  • Protected persons referred to in articles L1121-6 and L1121-8 of French public health code (deprived of liberty, tutorship or curatorship)
  • The patient already enrolled in the study

Treatment and study plan

Pleuropulmonary ultrasound performed by the investigator for patient with suspicion od Pneumonia

Procedure

In addition to the traditional management done by the physician at the patient's expense (such as clinical examination and paraclinical examinations like biology, chest X-ray, etc.), the investigator will perform pleuropulmonary ultrasound.

Primary outcomes

  1. Time between the antibiotic prescription and the pleuropulmonary ultrasonography used to detect pneumonia

    Time frame: 1 hour

    Time between the antibiotic prescription and the pleuropulmonary ultrasonography used to detect pneumonia

Secondary outcomes

  1. Calculation of the predictive values of the pleuropulmonary ultrasound for pneumonia diagnosis

    Time frame: 1 day

    Calculation of the predictive values of the pleuropulmonary ultrasound for pneumonia diagnosis: area under the curve, sensitivity, specificity, positive predictive value, negative predictive value.

  2. duration of performing the pleuropulmonary ultrasound

    Time frame: 5 minutes

    duration of performing the pleuropulmonary ultrasound

  3. Time between the patient's admission to the emergency department and the completion of the pleuropulmonary ultrasound

    Time frame: 1 hour

    Time between the patient's admission to the emergency department and the completion of the pleuropulmonary ultrasound

  4. 4. Time between the performance of the pleuropulmonary ultrasound and the performance of the chest X-ray

    Time frame: 2 hours

    • Time between the performance of the pleuropulmonary ultrasound and the performance of the chest X-ray

Study contacts

Contact information is provided by the study sponsor or research team.

Alice GREMBER, MD

CONTACT

[email protected]

0033476766784

Marcelline BUFFIN

CONTACT

[email protected]

0033476766784

Sponsors and collaborators

Lead sponsor

University Hospital, Grenoble

Other

Registry information

Acronym: PRE-EPPA

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 14, 2026
Registry last updated
Jul 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.