Pilot Study of Imaging Human Skin With High-Speed Spectrally Encoded Confocal Microscopy

SECM provides an order of magnitude faster imaging speed than conventional confocal microscopy devices. The investigators have previously utilized the SECM technology for imaging large area of human esophagus in vivo. They have also developed endoscopic capsule devices which have been used to safely image over 60 human subjects, healthy volunteers and subjects with eosinophilic esophagitis, using SECM technology, rapidly.

When used for skin imaging, SECM can provide real-time three-dimensional confocal imaging and significantly reduce the imaging time. While SECM has been successfully used for imaging human esophagus in vivo, its utility in skin imaging needs to be tested in a new pilot study. The investigators will be taking images with a dermatoscope as well. This will the control to compare the experimental images to, as the dermatoscope is the standard of care diagnostic tool for dermatologists.

Inclusion criteria

• Healthy adults
• 18 years of age or older
• Capable of giving informed consent
• Pigmented lesions (such as moles) present on the forearm

Exclusion criteria

• Unable to provide consent
• Open cuts/sores on the skin, skin infection, or any contagious skin condition
• Pregnant women (according to subject)
• Employees under the direct supervision of the investigator