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NCT Number: NCT07599462

Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes

The study is a pilot test of effectiveness of communication campaign ads on interest in quitting combustible cigarettes and e-cigarettes. Over the course of 5 weeks, participants are sent ads that are designed to encourage quitting and then answer surveys.

Recruiting

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Key information

Conditions

Tobacco Products Behavior Cigarettes Electronic Cigarettes Smoking Vaping

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Recruitment is online and national, using existing Qualtrics survey panels

Chapel Hill, North Carolina, 27599, United States

Location status: Recruiting

Location contact

M. Justin Byron, PhD

CONTACT

[email protected]

919-966-3292

About this study

Qualtrics Services will enroll 90 US adult dual users to participate in this study using existing panels. Inclusion criteria are current cigarette and e-cigarette use, age 18 or older, and ability read and answer questions in English, and willingness to receive text messages. Qualtrics will contact, screen, consent and randomize participants into 1 of 2 study arms: exposure to a 3 cycles of 6 ads encouraging them to quit smoking and vaping simultaneously or 6 ads encouraging them to quit sequentially (quitting smoking first followed by quitting vaping). The ads (one per day) are presented along with brief daily surveys. The primary outcome in intent to quit smoking.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • use cigarettes every day or some days
  • use e-cigarettes every day or some days
  • age 18 or older
  • ability to read and answer questions in English

Exclusion criteria

  • under age 18

Treatment and study plan

Communication

Other

Participants view an image that is an ad designed to encourage them to quit their use of cigarettes and e-cigarettes.

Other names: advertising

Primary outcomes

  1. Cigarette quit intention

    Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)

    A three question scale of interest in quitting cigarettes: How [interested are you in quitting / likely are you to quit / much do you intend to quit] smoking cigarettes in the next 6 months? 4 point response scale.

Secondary outcomes

  1. E-cigarette quit intention

    Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)

    A three question scale of interest in quitting vaping (e-cigarettes): How [interested are you in quitting / likely are you to quit / much do you intend to quit] vaping in the next 6 months? 4 point response scale.

  2. Cigarette quit attempts

    Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)

    A question: In the last 7 days, have you attempted to stop smoking cigarettes? (yes/no)

  3. E-cigarette quit attempts

    Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)

    A question: In the last 7 days, have you attempted to stop vaping? (yes/no)

  4. Forgoing cigarettes

    Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)

    A question: In the last 7 days, how many times did you stop yourself from having a cigarette because you wanted to smoke less? [numerical response 0-250]

  5. Forgoing e-cigarettes

    Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)

    A question: In the last 7 days, how many times did you stop yourself from vaping because you wanted to smoke less? [numerical response 0-250]

Study contacts

Contact information is provided by the study sponsor or research team.

M. Justin Byron, PhD

CONTACT

[email protected]

919-966-3292

Sponsors and collaborators

Lead sponsor

UNC Lineberger Comprehensive Cancer Center

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

Designing and Evaluating Communication for Dual Users of E-cigarettes and Combustible Cigarettes

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 20, 2026
Registry last updated
Jul 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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