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Completed

NCT Number: NCT02827383

Pilot Stair Climbing Study

This pilot study seeks to demonstrate feasibility to conduct data collection and illustrate potential for effect of fractionalized bouts of stair climbing on glucose control in adults at risk for type 2 diabetes.

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Key information

Age range

40 year–64 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Clinical and Translational Research Unit, University of Georgia

Athens, Georgia, 30602, United States

About this study

Objective: Compare the short-term effects of two different fractionalized stair climbing bout protocols on glucose control among adults at risk for type 2 diabetes.

Rationale: Fractionalized physical activity is associated with reduced BMI, glycated hemoglobin, lower 2-hr plasma glucose and insulin sensitivity in cross-sectional studies. Yet, few studies have examined the effects of fractionalized or intermittent physical activity in a prospective manner. Furthermore, the research is limited to patients with diagnosed type 2 diabetes, or using exercise of a moderate intensity.

The hypothesis is that stair climbing, a vigorous-intensity activity, may have a greater health effect. However, this has not been tested in short bouts of activity that are spread out during a day.

Implications: Fractionalized physical activity may be more feasible for adults at risk for, or with diagnosed type 2 diabetes who are not currently active. These short bouts can increase energy expenditure throughout the day, rather than in one long continuous bout as currently recommended.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age greater than 40 years but less than 65 years (working age adult with reduce physiologic capacity to regulate glucose)
  • BMI of overweight or obese (25.0 to 35.0)
  • Answered "No" to all questions on the Physical Activity Readiness Questionnaire, or has physician approval to participate
  • Hemoglobin A1C% value in the at-risk range of 5.7 to 6.4

Exclusion criteria

  • Unable to physically perform stair climbing
  • Currently exercising for 60 or more minutes weekly.
  • Weight over 275 lbs (because stair climbing machine has a weight limit)

Treatment and study plan

Stair Climbing Frequency

Behavioral

Includes 1 sedentary day prior to completing crossover phases.

Primary outcomes

  1. Continuous Glucose Monitor

    Time frame: Up to 5 days

    Participant has device inserted prior to dinner the night before the sedentary day, completes the sedentary day and two stair climbing days, then has the device removed on the morning of the 5th day.

Secondary outcomes

  1. Heart Rate

    Time frame: 2 Intervention Days

    Measuring heart rate during stair climbing for % max heart rate and % heart rate reserve. Heart rate will be measured during the stair climbing bouts on each of the two intervention days.

Sponsors and collaborators

Lead sponsor

Jennifer Gay

Other

Collaborators

  • University of Illinois at Urbana-Champaign

Registry information

Official study title

Pilot Study to Test the Effect of Fractionalized Vigorous-Intensity Activity on Acute Glucose in Adults at Risk for Type 2 Diabetes

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Jul 11, 2016
Registry last updated
Oct 25, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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