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Completed

NCT Number: NCT06524089

Pilates Versus Eccentric Exercises on Multiple Sclerosis

This study aims to determine whether Pilates-based stability or eccentric training is more effective for patients with multiple sclerosis(MS) with chronic non-specific low back pain(NSLBP).

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Back Pain Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Low Back Pain Nervous System Diseases Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo university hospital

Giza, 12625, Egypt

About this study

Thirty adult patients with multiple sclerosis with chronic NSLBP verified diagnosis of MS by a specialized neurologist will be questioned and screened according to inclusion and exclusion criteria.

Patients were randomly allocated to one of two groups: (Pilates or Eccentric). Every individual in both groups will be examined before and after the 6-week treatment program.

The handheld dynamometer assessed isometric trunk flexion and extension strength Pain intensity by casual analog scale (VAS). The Trunk Impairment Scale (TIS) evaluates static and dynamic sitting balance and trunk coordination in a seated position.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age range 18 to 40 years.
  • Relapsing-remitting free for at least 90 days before testing.

Exclusion criteria

  • Having a neurologic disease other than MS.
  • A relapse within 3 months.

Treatment and study plan

Pilate training

Other

Pilates based training exercises group will perform Pilates divided into two levels (beginner and intermediate). Each level will last for six sessions.

Eccentric training

Other

eccentric trunk training exercises group:The course of the intervention period is 12 sessions total, exercises performed for two to three sets with 10 to 15 repetitions each set and 2 min rest between each set

Primary outcomes

  1. pain intensity

    Time frame: At baseline and after 6 week

    VAS for measuring pain severity

  2. Function

    Time frame: At baseline and after 6 week

    The Trunk impairment scale (TIS) The static subscale investigates: (1) the ability of the subject to maintain a sitting position with feet supported; (2) the ability to maintain a sitting position while the legs are passively crossed, and (3) the ability to maintain a sitting position when the subject crosses the legs actively. The dynamic subscale contains items on lateral flexion of the trunk and unilateral lifting of the hip. To assess the coordination of the trunk, the subject is asked to rotate the upper or lower part of his or her trunk 6 times, initiating the movements either from the shoulder girdle or from the pelvic girdle, respectively. For each item, a 2-, 3- or 4- point ordinal scale is used. On the static and dynamic sitting balance and coordination subscales the maximal scores that can be attained are 7, 10 and 6 points. Therefore, TIS ranges between 0 for a minimal performance to 23 for a perfect performance.

Secondary outcomes

  1. back muscle strength

    Time frame: At baseline and after 6 week

    Handheld dynamometer measuring isometric trunk muscle strength

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Pilates Versus Eccentric Exercises in Chronic Low Back Pain With Multiple Sclerosis

Acronym: MS

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 29, 2024
Registry last updated
Mar 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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