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Completed

NCT Number: NCT00232427

PiCCO Guided Therapy in Liver Cirrhosis

Prospective comparison of standard therapy in liver cirrhosis versus standard therapy plus intensified hemodynamic monitoring using the PiCCO system.

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Key information

Conditions

Liver Cirrhosis Digestive System Diseases Fibrosis Liver Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Heidelberg, Clinical center

Heidelberg, 69120, Germany

About this study

Patients presenting with advanced liver cirrhosis will receive either standard treatment or standard treatment plus hemodynamic monitoring with the PiCCO device. Fluids and vasoacitve drugs will be administered according to the measurements over a period of 5 days.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Liver cirrhosis Child-Pugh-Score > 7
  • Ascites > 500 ml

Exclusion criteria

  • Coronary heart disease
  • Apoplexia < 6 months ago
  • Vasculitis
  • Thrombosis
  • Arterial occlusive disease > stadium II

Treatment and study plan

Hemodynamic monitoring system PiCCO

Procedure

Primary outcomes

  1. Survival

Secondary outcomes

  1. Renal complications

  2. Length of intensive care

  3. Change in APACHE II

Sponsors and collaborators

Lead sponsor

Heidelberg University

Other

Registry information

Official study title

Optimized Therapy of Decompensated Liver Cirrhosis by Hemodynamic Monitoring Using the PiCCO System

Important dates

Study start
2005
Study completion
2007
First posted
Oct 4, 2005
Registry last updated
Oct 3, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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