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NCT Number: NCT07127783

Physical Therapy After Endometriosis Excision

This is a randomized controlled pilot study comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy. Quality of life and endometriosis symptoms will be compared following the recovery period.

Recruiting

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Key information

Age range

18 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Oregon Health & Science University

Portland, Oregon, 97239, United States

Location status: Recruiting

Location contact

Jacqueline Wong

PRINCIPAL_INVESTIGATOR

Women's Health Research Unit

CONTACT

[email protected]

503-494-3666

About this study

This is a randomized controlled pilot study conducted at a single institution comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy. Patients will be recruited from a referral gynecological surgery group specializing in the diagnosis and treatment of pelvic pain and endometriosis. The goal is to assess the role of the active recovery program on quality of life and on pain and endometriosis symptoms.

Subjects will be randomized to routine post-operative care or to a home physical therapy program, in which they will receive written instruct ions and videos of exercises to complete immediately after surgery. The home exercise program was developed by the Department of Urogynecology in conjunction with pelvic floor physical therapists, and includes videos created by the education communications division. Quality of life, pain score, and endometriosis symptoms will be assessed at their pre-operative appointment, and at 6 and 12 weeks postoperatively.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Premenopausal
  • English speaking
  • Undergoing endometriosis excision surgery without hysterectomy at Legacy Health with subspecialty-trained surgeons specializing in endometriosis care
  • History of chronic pelvic pain (defined as >= 6 months of pain in the anatomic pelvis)
  • Diagnosis of high tone pelvic floor dysfunction on examiniation
  • Have access to reliable email and phone for study-related communication

Exclusion criteria

  • Non-English speaking
  • Unable to consent
  • Unable to sustain 30 minutes of moderate activity at baseline
  • Uses a mobility assistive device at baseline
  • Chronic opioid use
  • No histologic diagnosis of endometriosis on surgical pathology
  • Need for additional pelvic rest (>2 weeks) postoperatively
  • Pregnancy or planning to pursue pregnancy or undergo fertility treatments within 12 weeks postoperatively

Treatment and study plan

Active Recovery

Behavioral

Participants will receive postoperative instructions to follow an active recovery protocol focused on increasing activity level, core strength exercises, and pelvic floor exercises focused on urinary and bowel symptoms. Exercises are to be completed twice per day for the 12 weeks following surgery.

Standard Postoperative Instructions

Behavioral

Standard of care postoperative instructions covering incision care, pain control, dietary instructions, and emergency precautions. Also includes guidelines regarding pelvic rest and lifting restrictions.

Primary outcomes

  1. Short Form Survey (SF-36)

    Time frame: Collected immediately following surgery, 6 weeks following surgery, and 12 weeks following surgery

    The Short Form Survey (SF-36) is a 36-item survey regarding general health and pain and its impact on quality of life including physical activities, work, social activities, and emotional well-being over the last four weeks. Scores range from 0 to 100 with a higher score representing a more favorable health state.

  2. Pelvic Floor Impact Questionnaire (PFIQ)

    Time frame: Collected immediately following surgery and 12 weeks following surgery

    The Pelvic Floor Impact Questionnaire (PFIQ) asks about how bladder, bowel, and pelvic symptoms affect the ability to do physical activities as well as their impact on emotional well-being over the last 3 months. Scores range from 0 to 300 with a lower score representing a lesser impact on quality of life.

Secondary outcomes

  1. Pain Scores

    Time frame: Collected at baseline, 6 weeks following surgery, and 12 weeks following surgery.

    Pain measured using a Visual Analog Scale (VAS). This scale asks patients to rate their pelvic pain and dyspareunia over the last 4 weeks. Responses are on a scale from 0 to 10, with 10 being the worst pain.

  2. Endometriosis Health Profile (EHP-5)

    Time frame: Collected at baseline, 6 weeks following surgery, and 12 weeks following surgery.

    The Endometriosis Health Profile (EHP-5) is a 5-item questionnaire asking about the perception of endometriosis symptoms on physical ability, emotional well-being, mood, social isolation, and appearance over the last four weeks. Scores range from 0 to 100 where 0 indicates the best health status.

Study contacts

Contact information is provided by the study sponsor or research team.

Women's Health Research Unit Department of Ob/Gyn

CONTACT

[email protected]

503-494-3666

Sponsors and collaborators

Lead sponsor

Oregon Health and Science University

Other

Registry information

Official study title

The Role of a Postoperative Home Physical Therapy Program for the Treatment of Pelvic Pain in Patients Undergoing Endometriosis Excision

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 17, 2025
Registry last updated
Oct 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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