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NCT Number: NCT07652502

Physical Exercise During the Cancer Care Pathway

Background: Physical exercise is proven safe and effective in improving quality of life and reducing treatment-related side effects in oncology. However, patient adherence to international guidelines remains suboptimal. Investigating the knowledge, attitudes, and practices (KAP) regarding physical activity is crucial to identifying unmet educational needs and barriers.

Objective: This multicenter, cross-sectional observational study (ECOLE project) aims to assess KAP levels concerning exercise among cancer patients and explore the correlations between KAP scores and sociodemographic or clinical variables.

Methods: Over a 6-month period, an anonymous online survey (Microsoft Forms) will be administered to adult cancer patients (≥18 years old) at any disease or treatment stage. A minimum sample size of 370 participants is targeted. Statistical analyses will include Descriptive Statistics, Exploratory and Confirmatory Factor Analyses to validate KAP scales, and Multivariable Logistic Regression to identify predictors of adherence (≥150 minutes/week) and perceived barriers or facilitators.

Expected Results: The study will provide a comprehensive overview of physical activity perceptions and behaviors in oncology. These insights will support the design of targeted educational interventions and structured exercise programs, contributing to the development of a novel "Exercise Oncology Specialist" within supportive care teams.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Institut Rafael, Paris, France

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years
  • Oncological diagnosis
  • Ability to understand the language of the respective country of origin
  • Electronic informed consent

Exclusion criteria

  • Failure to accept the informed consent

Treatment and study plan

Primary outcomes

  1. physical exercise in cancer patients.

    Time frame: 1 day

    To evaluate the level of knowledge, attitudes, and practices (KAP) related to physical by administering the study survey exercise in cancer patients.

Secondary outcomes

  1. safety of physical exercise oncology

    Time frame: 1 day

    Determine the level of knowledge regarding the benefits and safety of physical exercise by administering the study survey.

  2. self-efficacy regarding exercise oncology

    Time frame: 1 day

    Evaluate attitudes, perceptions, and self-efficacy regarding physical activity by administering the study survey.

  3. relationship between exercise oncology and oncological journey

    Time frame: 1 day

    Analyze the potential relationship between knowledge, attitudes, and the practice of physical exercise

  4. demographic and clinical variables in exercise oncology

    Time frame: 1 day

    Explore the role of demographic and clinical variables (e.g., age, sex, tumor type, phase of treatment) by administering the study questionnaire.

  5. barriers and facilitators to exercise oncology

    Time frame: 1 day

    Identify potential barriers and facilitators to the practice of physical exercise by administering the study questionnaire.

  6. interest of cancer patients in exercise oncology

    Time frame: 1 day

    Assess the interest of cancer patients in structured physical exercise programs by administering the study questionnaire.

Study contacts

Contact information is provided by the study sponsor or research team.

Stefano Magno

CONTACT

[email protected]

+390630157077

Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Acronym: ECOLE

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Jun 17, 2026
Registry last updated
Jun 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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