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Completed

NCT Number: NCT02304731

Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects

Modern society increasingly seeks healthy life style, and regular physical activity is considered one of the main factors that improve the quality of life. The evidence shows that the aerobic physical training in controlled environments benefit various aspects of human health, including cognition in the elderly population. However, when exercise is performed in a polluted environment, the individual is subjected to grater exposure to pollutants due to increased ventilation (breathing).

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

About this study

Modern society increasingly seeks healthy life style, and regular physical activity is considered one of the main factors that improve the quality of life. The evidence shows that the aerobic physical training in controlled environments benefit various aspects of human health, including cognition in the elderly population. However, when exercise is performed in a polluted environment, the individual is subjected to grater exposure to pollutants due to increased ventilation (breathing). It is well known that inhaled pollutants can cause oxidative modification in biomolecules and oxidative stress is a cause of diverse diseases. This scenario raises important questions: the deleterious effects of pollution can abolish the beneficial effects of exercise? This issue is currently relevant given the increasing level of air pollution in large urban centers such as Sao Paulo city and at the same time, outdoor physical activity in public places is largely stimulated by public organizations, particularly for elderly. Thus this multidisciplinary project aims to investigate the deleterious effects of urban air pollution in elderly people who practice aerobic physical exercise outdoors in Sao Paulo and compare with those who practice in Laboratory. This study can provide important knowledge for public health and welfare of the population.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Health Subjects that lives in São Paulo city for at least 10 years.

-

Exclusion criteria

Neuropsychological issues.

-

Treatment and study plan

Physical exercise

Other

Incremental running

Primary outcomes

  1. Cognitive Benefits

    Time frame: 12 weeks

    Neuropsychological Tests applied at the beginning and at the end of protocol

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Collaborators

  • University of Sao Paulo

Registry information

Official study title

Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects.

Important dates

Study start
2013
Primary completion
2013
Study completion
2014
First posted
Dec 2, 2014
Registry last updated
Dec 2, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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