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Completed

NCT Number: NCT07670208

Physical Activity Promoting Active Aging

This project aims to explore the effects and underlying mechanisms of physical activity in promoting active aging among older adults. The researchers conducted two rounds of progressive randomized controlled intervention trials to verify the effects and mechanisms of a multimodal physical activity intervention on active aging from two dimensions: intervention structure and participation mode.

In Study 1, with a 12-week intervention period, participants were randomly assigned to three groups: a Tai Chi exercise group, a multimodal exercise group, and a daily activity control group. By comparing between-group differences, the study evaluated the effects of different exercise modalities on physical function and subjective active aging.

In Study 2, also with a 12-week intervention period, participants were randomly assigned to two multimodal exercise groups differing in participation mode: an in-person group-based format versus an online individual format. This study examined the moderating effects of different participation modes on both objective and subjective active aging outcomes, while keeping the multimodal physical activity intervention content identical.

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Key information

Age range

60 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Sports Science, College of Education, Zhejiang University

Hangzhou, Zhejiang, 310058, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 60 years or above;

Capable of engaging in regular physical activities and comprehending basic testing procedures and instructions.

Exclusion criteria

  • Severe cardiac, pulmonary, or musculoskeletal disorders;

History of neurological or psychiatric conditions that may impair cognitive function (e.g., stroke, Parkinson's disease, Alzheimer's disease, major depressive disorder, etc.);

Missing three or more scheduled intervention sessions during the study period, or requesting discontinuation of participation.

Treatment and study plan

Mind-body exercise

Behavioral

Tai Chi, Yoga, and Baduanjin

multicomponent exercise

Behavioral

Tai Chi, Baduanjin, strength, balance, and flexibility exercises

Online-based multicomponent exercise

Behavioral

Tai Chi, Baduanjin, and strength, balance, and flexibility exercises (delivered via live online streaming and video watching)

In-person multicomponent exercise

Behavioral

Tai Chi, Baduanjin, and strength, balance, and flexibility exercises (delivered in an in-person group format)

Primary outcomes

  1. Active aging

    Time frame: week0, week6, week12

    It was measured using the Active Aging Questionnaire.

  2. General self-efficacy

    Time frame: week0, week6, week12

    It was measured using the General Self-Efficacy Scale.

  3. Cognitive function

    Time frame: week0, week6, week12

    Cognitive function was measured using the cognitive subscale of the LEIPAD questionnaire

  4. Cognitive function assessed by the Montreal Cognitive Assessment (MOCA)

    Time frame: week0, week6, week12

    Cognitive function was measured using the Montreal Cognitive Assessment (MOCA).

Secondary outcomes

  1. Height

    Time frame: week0, week6, week12

  2. Weight

    Time frame: week0, week6, week12

  3. Body fat percentage

    Time frame: week0, week6, week12

  4. Vital capacity test

    Time frame: week0, week6, week12

    Physiological parameter

  5. 2-minute high-knee marching in place

    Time frame: week0, week6, week12

  6. Handgrip strength

    Time frame: week0, week6, week12

  7. Sit and reach test

    Time frame: week0, week6, week12

  8. 30-second chair stand test

    Time frame: week0, week6, week12

    Physiological parameter

  9. One-legged stance with eyes closed tesr

    Time frame: week0, week6, week12

    Physiological parameter

  10. Choice reaction time

    Time frame: week0, week6, week12

Sponsors and collaborators

Lead sponsor

Yu Wang

Other

Registry information

Official study title

Physical Activity Promoting Active Aging: An Exploration of Intrinsic Mechanisms and Practical Pathways

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 26, 2026
Registry last updated
Jun 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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