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OpenTrials
Completed

NCT Number: NCT00739180

Physical Activity in Youth: Implications for Reversing Risk Factors for Type 2 Diabetes

In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, and risk of type 2 diabetes in overweight children and adolescents.

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Key information

Conditions

Abdominal Obesity Body Weight Digestive System Diseases Fatty Liver Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Liver Diseases Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Obesity, Abdominal Overnutrition Overweight Pathological Conditions, Signs and Symptoms Pediatric Obesity Signs and Symptoms

Age range

12 year–18 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine

Pittsburgh, Pennsylvania, 15213, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy overweight (BMI >-95th) youth between 12 and 18 years of age
  • Waist circumference >-75th percentile
  • Sedentary (no structured exercise >2 times/week for past 6 months)
  • Non-smokers, non-diabetic, no medical conditions
  • Weight stable for past 3 months

Exclusion criteria

  • Smokers,
  • diabetic,
  • psychiatric disorders,
  • syndromatic obesity

Treatment and study plan

Control

Other

Standard care control (no exercise)

Resistance Exercise

Other

Supervised resistance exercise using stack weight equipments.

Aerobic Exercise

Other

Supervised aerobic exercise using treadmills, bikes, and ellipticals

Primary outcomes

  1. Abdominal obesity, visceral fat

    Time frame: 3 month

Secondary outcomes

  1. Insulin sensitivity and secretion, glucose tolerance

    Time frame: 3 month

Sponsors and collaborators

Lead sponsor

University of Pittsburgh

Other

Collaborators

  • American Diabetes Association

Registry information

Important dates

Study start
2007
Primary completion
2011
Study completion
2011
First posted
Aug 21, 2008
Registry last updated
Nov 6, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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