IROC
Zurich, Canton of Zurich, 8002, Switzerland
NCT Number: NCT06978556
Modern cataract surgery has become a refractive procedure. Both, multifocal lens implantation and pseudophakic monovision with monofocal IOLs are effective means to address presbyopia correction after cataract surgery. Historically, diffractive multifocal IOLs have provided improved visual acuity at near and intermediate distances and a greater likelihood of spectacle independence than monofocal IOLs.
The light transmittance ratio of the crystalline lens is high and as a monofocal ocular medium that has the ability to modify its shape and geometric properties according to the focal point. Therefore, it is capable of delivering the exact same light energy to the retina, regardless of the distance of the object. Trifocal IOL designs split the light in three focal points. By varying the height of the diffractive step, the amount of light distributed to near, intermediate and distant foci is adjusted according to pupil aperture. The distribution of light to three different foci includes several potential disadvantages, such as loss of visual acuity in mesopic conditions and a loss of contrast sensitivity. Thus, the visual performance of multifocal IOLs depends on several factors, the addition (add) power is a major determinant of the actual range of clear vision, another factor is the light transmittance characteristics of the lens (e.g., the incorporation of a blue light filter).
As different trifocal IOLs become available, it is important to have information on their characteristics regarding visual acuity in order to be able to recommend an IOL that meets the individualized needs of each patient. In order to provide the patient with a high visual acuity in all promised distances, these IOLs need to be aimed at and achieve emmetropia.
Furthermore, multifocal IOLs need good capsular bag centration, they need to remain as unaffected as possible by capsular bag constriction and remain stable in their axial lens position in order to provide a stable refraction after surgery.
The investigators compare the anterior chamber depth stability as marker for positional stability and haptic buckling between two different diffractive IOL designs, one with C-loop haptics and one with plate haptics. Furthermore, the refractive outcome of these IOLs with different designs is examined in photopic and mesopic conditions, as well as visual acuity results for both IOLs.
This study is active but is not currently recruiting participants.
Notify Me45 year and older
All sexes
Observational
Zurich, Canton of Zurich, 8002, Switzerland
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
No intervention is subject of the study. Only standard pre- and postoperative data will be evaluated. Including data from testing refraction, visual acuity, biometry, tomography, and OCT.
Time frame: 1, 3, 6, 12 months
as measured with a biometry and/or anterior segment device.
Time frame: 1, 3, 6, 12 months
standardized ETDRS charts Optometrist blinded
Time frame: 1, 3, 6, 12 months
Standardized with ETDRS charts for far, intermediate, and far distance visual acuity. Defocus curve.
Optometris is blinded. Measurement in photopic and mesopic conditions
Time frame: 3 months
standardized with iRest test. In photopic and mesopic conditions.
optometrist is blinded.
IROC AG
Other
Comparison of Lens Position and Photopic and Mesopic Visual Acuity After Bilateral Implantation of Two Different Diffractive Multifocal Intraocular Lenses.
Acronym: MIOLRead
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07008768
Cataract, Eye Diseases
Zagreb, Croatia
View Trial DetailsNCT03844828
Cataract, Eye Diseases
Makati City, Philippines
View Trial DetailsNCT04570579
Cataract, Cataract Senile
Babylon, New York, United States
View Trial DetailsNCT05411341
Cataract, Eye Diseases
Alexandroupoli, Evros, Greece
View Trial Details