Photonic Needle and Paravertebral Space Detection

The primary objective of the trial is to investigate if the photonic needle technology can reliably identify the thoracic paravertebral space. Diffuse reflectance spectra will be acquired during needle advancement, with custom-made needle stylets that contain optical fibers.

Main study parameters are:

• Successfully acquired diffuse reflectance spectra obtained in the thoracic paravertebral space, and spectra obtained during needle advancement.
• Confirmation of sonographic thoracic paravertebral localization, defined as tissue imaging in all locations of the needle where the diffuse reflectance spectra have been collected .
• Recordings of reaction to a small test dose of lidocaine 2% with epinephrine 1:200.000 at target position for regional anesthesia (to exclude vascular localization of the needle)
• "certainty score" on a 3-point scale (1 = uncertain, 2 = certain, 3 = very certain) provided by the physician for assignment of the type of tissue present at the needle tip, based on the information available from imaging and/or aspiration and/or reaction to a small injection of epinephrineOther study parameters

The endpoint of the study is a statistical analysis of the difference between diffuse reflectance spectra obtained at non-paravertebral and paravertebral measurement locations.

Inclusion criteria

• Elective unilateral thoracic surgery
• Age between 18 and 80 years of age
• Ability and willingness to provide informed consent

Exclusion criteria

• Pregnancy
• Photodynamic therapy
• Contraindications to regional anesthesia and/or allergy to amide local anesthetics.
• Subjects < 18 years of age or >80 years of age
• Severe coagulopathy
• Subjects with severe thoracic deformities
• Subjects with contraindications to methylene blue