Phosphorous Magnetic Resonance Spectroscopy of Heart

Heart needs constant supply of energy to continue working. Phosphorus magnetic resonance spectroscopy allows us to measure energy produced in the heart. The purpose of this study is to determine if the energy production is reduced in failing heart.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Left Ventricular Dysfunction Cardiovascular Diseases Heart Diseases Ventricular Dysfunction Ventricular Dysfunction, Left

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Washington University in St. Louis

St Louis, Missouri, 63110, United States

About this study

We will use non-invasive phosphorus magnetic resonance spectroscopy technique to measure creatine kinase (CK) flux in failing heart. The studies will be done on Siemens 3.0T human system. We will recruit subjects with LV dysfunction due to prior anterior wall myocardial infarction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Individuals with left ventricular dysfunction

Exclusion criteria

Age < 18, pregnant, history of excessive alcohol use, or any condition (e.g. claustrophobia, a pacemaker) that would prevent him/her from completing the magnetic resonance spectroscopy study

Treatment and study plan

MR Spectroscopy

Diagnostic Test

MR spectroscopy of myocardial

Primary outcomes

An MR Spectroscopy Showing Signal to Noise Ratio to Determine the Level of Heart Failure

Time frame: 1-2 days

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Registry information

Official study title

31P Magnetic Resonance Spectroscopy of Heart

Important dates

Study start: 2009
Primary completion: 2011
Study completion: 2011
First posted: Apr 26, 2010
Registry last updated: Aug 7, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed