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OpenTrials
Completed

NCT Number: NCT00069706

Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patients

The purpose of this study is to determine the safety and IOP-lowering ability of a glaucoma therapy in patients with open-angle glaucoma or ocular hypertension.

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Key information

Conditions

Open-angle Glaucoma Cardiovascular Diseases Eye Diseases Glaucoma Glaucoma, Open-Angle Hypertension Ocular Hypertension Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years or older.
  • Diagnosis of open-angle glaucoma or ocular hypertension.
  • LogMAR visual acuity not worse than 0.6.
  • Other protocol-defined inclusion criteria may apply.

Exclusion criteria

  • Clinically relevant ophthalmic or systemic conditions.
  • Other protocol-defined exclusion criteria may apply.

Treatment and study plan

AL-12182 0.003% Ophthalmic Solution

Drug

Investigational ophthalmic solution intended for the treatment of open-angle glaucoma or ocular hypertension

AL-12182 Ophthalmic Solution Vehicle

Other

Placebo

Latanoprost 0.005% Ophthalmic Solution

Drug

Commercially marketed ophthalmic solution intended for the treatment of open-angle glaucoma or ocular hypertension

AL-12182 0.01% Ophthalmic Solution

Drug

Investigational ophthalmic solution intended for the treatment of open-angle glaucoma or ocular hypertension

AL-12182 0.03% Ophthalmic Solution

Drug

Investigational ophthalmic solution intended for the treatment of open-angle glaucoma or ocular hypertension

Primary outcomes

  1. Mean Intraocular Pressure (IOP)

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Important dates

Study start
2003
Primary completion
2003
Study completion
2003
First posted
Oct 6, 2003
Registry last updated
Feb 14, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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