PG Versus TG for Advanced PGC

We conducted a retrospective study on patients with pathological stage II-III PGC who underwent PG or TG from 2013 to 2023. Propensity score-matching was applied to adjust for tumor size and stage between the PG and TG groups at a 1:1 ratio. We evaluated the procedural safety, oncological, and functional outcomes.

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Key information

Conditions

Gastric Adenocarcinoma Gastrectomy

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National Taiwan University Hospital Hsin-Chu Branch

Hsin-Chu County, 302, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Proximal gastric adenocarcinoma after total or proximal gastrectomy.

Exclusion criteria

Non-curative resections
Non-adenocarcinoma histology
Distally located tumors or middle/proximally located tumors for which distal margin could not be secured by PG
Remnant gastric cancer
Clinically T1N0 tumors smaller than 3 cm for which PG was clearly indicated

Treatment and study plan

proximal gastrectomy

Procedure

proximal gastrectomy

total gastrectomy

Procedure

total gastrectomy

Primary outcomes

five-year overall survival

Time frame: 5 years

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

Proximal Versus Total Gastrectomy for Advanced Proximal Gastric Cancer: A Retrospective Double-Center Propensity Score-Matched Cohort Study

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Sep 26, 2024
Registry last updated: Nov 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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