Department of Nuclear Medicine,Xijing Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China
NCT Number: NCT06914427
This is a study using a parallel control approach and is expected to recruit 35 volunteers, including 8 prostate cancer patients, 8 neuroendocrine tumour patients, 8 glioma patients, 8 Parkinson's syndrome patients, and 3 normal volunteers, to undergo dual-nuclide PET/CT imaging and to validate the isolation effect and quantitative accuracy of simultaneous dual-nuclide imaging in humans.
Trial opening soon.
Get Notified18 year–75 year
All sexes
Interventional
Not applicable
Xi'an, Shaanxi, China
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Subjects can fully understand and voluntarily participate in this experiment and sign an informed consent form.
Exclusion criteria
Scanning time: acquisition starts 60±10 minutes after 68Ga/18F probe injection; 10-20 minutes after 11C-MET injection; 60 minutes after 11C-CFT injection; Scanning parameters: whole-body imaging (cranial vault to mid-thigh), routine single-nuclide 3 min/bed; dual-nuclide 5-10 min/bed.
Time frame: 1 day from injection of the tracer
using the 68Ga, 11C, 18F individual imaging images as the gold standard and calculating the retention of the letter lesion area number on the 68Ga/18F and 11C/18F separate images
Time frame: 1 day from injection of the tracer
calculated by using the 68Ga, 11C and 18F individual imaging images as the gold standard, and calculating the signal clearance of the lesion area on the 18F/68Ga and 18F/11C separate images
Time frame: 1 day from injection of the tracer
paired t-test comparing the difference in SUVmax values of lesions on gold standard versus 68Ga/18F and 11C/18F separation images
Contact information is provided by the study sponsor or research team.
Xijing Hospital
Other
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