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NCT Number: NCT07532382

Personalized Stories for Pediatric Kidney Recipients

Pediatric kidney transplant recipients often face major psychosocial challenges that are difficult to address with existing tools. This study evaluates whether clinically supervised AI can generate personalized, age-adapted therapeutic stories for these children and their families.

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Key information

Conditions

Kidney Transplant

Age range

5 year–12 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Necker hospital

Paris, Île-de-France Region, 75015, France

Location status: Recruiting

Location contact

Evgenia Preka, MD, PhD

CONTACT

[email protected]

+33144494000

About this study

Pediatric kidney transplant recipients face substantial psychosocial challenges, including anxiety, fear, difficulty understanding complex medical experiences, and challenges returning to school and social life. Therapeutic storytelling may help children process these experiences, but truly personalized stories are difficult to produce manually at scale. Large language models offer the opportunity to generate age-adapted, personalized, and clinically supervised stories. This study aims to develop and evaluate an AI-assisted storytelling workflow for pediatric kidney recipients and their families.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 5-12 years inclusive at enrolment.
  • Recipient of a kidney transplant.
  • Clinically stable at enrolment (no active rejection, acute infection, or current hospitalization for a graft-related complication).
  • Fluency in French or English.
  • Written informed consent from parent(s)/legal guardian(s); child assent when age-appropriate.

Exclusion criteria

  • Severe cognitive impairment precluding engagement with narrative content.
  • Mental state not allowing participation.
  • Family unwilling or unable to commit to the study timeline and interview requirements.

Treatment and study plan

AI-generated story

Other

A story generated by artificial intelligence is created and personalized for pediatric kidney recipient

AI generated story

Other

This is a minimal-risk observational study. Families complete a questionnaire and receive an AI-generated, clinically supervised personalized story. During the pilot phase, there is no direct child-AI interaction. All stories are reviewed by the clinical lead before delivery.

Primary outcomes

  1. Child and family experience of the story after delivery.

    Time frame: One month after story delivery

    Child and family experience of the story, assessed through qualitative feedback, thematic analysis, and satisfaction ratings collected after story delivery.

  2. Child and family experience of the story after delivery.

    Time frame: One month after the story is delivered

    Child and family experience of the story, assessed through qualitative feedback, thematic analysis, and satisfaction ratings collected after story delivery.

Study contacts

Contact information is provided by the study sponsor or research team.

Marc Raynaud, PhD

CONTACT

[email protected]

+33613493009

Sponsors and collaborators

Lead sponsor

Paris Translational Research Center for Organ Transplantation

Other

Registry information

Official study title

Generating Personalized Stories With Artificial Intelligence for Pediatric Kidney Recipients

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 15, 2026
Registry last updated
Apr 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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