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OpenTrials
Completed

NCT Number: NCT04079972

Personalized Lifestyle Intervention and Weight Control

This trial aims to investigate whether tailored lifestyle consultation through SNP testing leads to more effective weight loss among overweight or obese individuals compared to general lifestyle guidance for weight control.

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Key information

Conditions

Weight Loss Body Weight Body Weight Changes Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dongguk University

Goyang-si, Gyeonggi-do, 10326, South Korea

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Korean adults aged 18 years and older who are interested in weight management through dietary and/or exercise therapy.
  • Individuals who are able and willing to participate consistently for the entire 2-year study period.

Exclusion criteria

  • Individuals with any illness requiring regular medical treatment in a hospital.
  • Individuals currently taking long-term prescribed medications.
  • Individuals diagnosed with eating disorders or mental illnesses (e.g., depression, panic disorder) by a physician.
  • Individuals who have undergone gastric surgery for weight loss.
  • Individuals who have undergone heart surgery or cancer surgery.
  • Individuals with severe anemia.
  • Individuals who are unable to engage in physical exercise.
  • Pregnant or breastfeeding women, or those planning to become pregnant within 2 years.

Treatment and study plan

Obesity-related genetic information disclosure with tailored lifestyle recommendations

Behavioral

They received their complete SNP results, including obesity-related traits, along with corresponding lifestyle recommendations.

Non-obesity-related genetic information disclosure

Behavioral

Provided only with genetic test results related to beauty traits at baseline; information on metabolic health-related SNPs was disclosed only after the final follow-up assessment.

Primary outcomes

  1. Body Weight (kg)

    Time frame: About 5 months after randomization and at study completion (~17 months)

    Change was calculated as the value at the later time point minus the value at baseline (i.e., value at about 5 months after randomization minus baseline, and value at study completion (~17 months) minus baseline). Positive values represent increases from baseline, and negative values represent decreases.

Secondary outcomes

  1. Body Fat Mass (kg)

    Time frame: About 5 months after randomization and at study completion (~17 months)

    Change was calculated as the value at the later time point minus the value at baseline (i.e., value at about 5 months after randomization minus baseline, and value at study completion (~17 months) minus baseline). Positive values represent increases from baseline, and negative values represent decreases.

  2. Body Fat Percentage (%)

    Time frame: About 5 months after randomization and at study completion (~17 months)

    Change was calculated as the value at the later time point minus the value at baseline (i.e., value at about 5 months after randomization minus baseline, and value at study completion (~17 months) minus baseline). Positive values represent increases from baseline, and negative values represent decreases.

  3. Skeletal Muscle Mass (kg)

    Time frame: About 5 months after randomization and at study completion (~17 months)

    Change was calculated as the value at the later time point minus the value at baseline (i.e., value at about 5 months after randomization minus baseline, and value at study completion (~17 months) minus baseline). Positive values represent increases from baseline, and negative values represent decreases.

Sponsors and collaborators

Lead sponsor

NaNa Keum

Other

Collaborators

  • DongGuk University
  • National Research Foundation of Korea

Registry information

Official study title

Personalized Lifestyle Intervention Based on SNP Testing and Weight Control

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Sep 6, 2019
Registry last updated
Jan 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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